A combined genotype including 10 markers was more frequent among the asymptomatic subjects (17%) than among patients (3%), and was associated with a reduction in fibrinogen antigen level (2·42±0·35 vs 2·69±0·41g/l, P =0·028) among the asymptomatic subjects. Our data suggest that...
The association between adverse pregnancy outcomes and maternal factor V Leiden genotype: a meta-analysis. Thromb Haemost 2004;91:700 –711. 92. Kovalevsky G, Gracia CR, Berlin JA, Sammel MD, Barnhart KT. Evalu- ation of the association between hereditary thrombophilias and recurrent pregnancy ...
We determined the factor V Leiden genotype in 471 consecutive patients aged less than 70 years with a first objectively confirmed deep-vein thrombosis and in 474 healthy controls. We found 85 heterozygous and seven homozygous individuals among the cases with thrombosis and 14 heterozygous individuals ...
After getting an 80% amplification success for amelogenin, a melting curve analysis using lightcycler was performed to determine the FVL genotype of each sample. Of the 60 samples, 1 gave a positive amplification result for FV gene and was found to be heterozygous. To date, the age of this ...
To examine whether the FVL allele is associated with pregnancy complications and adverse outcomes in a population-based study, and to identify potential factors that interact with the FVL genotype. Retrospective cohort study in a geographically-defined area. Polymorphisms of factor V 1691G-->A, ...
Synonyms for Factor V Leiden mutation in Free Thesaurus. Antonyms for Factor V Leiden mutation. 34 synonyms for mutation: anomaly, variation, deviant, freak of nature, change, variation, evolution, transformation, modification, alteration, deviation...
2.mutation- (genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism chromosomal mutation,genetic mutation genetic science,genetics- the branch of biology that studies heredity and variation in organisms ...
1. Factor V Leiden in an Urartian, dating back to 1000 BC. [J] . Alakoc YD, Aka PS, Egin Y, Clinical and applied thrombosis/hemostasis . 2010,第6期 机译:乌拉尔人时期的因子V莱顿,其历史可追溯到公元前1000年。 2. Factor V Leiden in an Urartian, Dating Back to 1000 BC [J] . ...
Women in the preeclampsia cohort (n=283) were genotyped for both the Leiden variant (G1691A) of factor V and the thermolabile variant (C677T) of methylenetetrahydrofolate reductase. Genotype and allele frequencies were compared with those of 2 control groups, one consisting of women recruited ...
studied.The live birth rate was significantly lower amongst women with a history of recurrent early miscarriage who carried the Factor V Leiden allele (6/16; 37.5%) compared with that amongst those with a normal Factor V genotype (106/153; 69.3%; odds ratio 3.75, 95% confidence intervals ...