Heterozygous Factor V Leiden deficiency with hepatic thrombosis in a twin pregnancy: a near missHepatic VeinsPregnancy, MultipleAdultFactor VFactor V DeficiencyFemaleHeterozygoteHumanPregnancyPregnancy Complications, CardiovascularDepartment of Obstetrics and Gynaecology, Hemel Hempstead General Hospital, Hemel ...
Genetic modulation of the FVLeiden/normal FV ratio and risk of venous thrombosis in factor V Leiden heterozygotes Genetic modulation of the FVLeiden/normal FV ratio and risk of venous thrombosis in factor V Leiden heterozygotes[J] . O.SEGERS,P.SIMIONI,D.TORMENE,... O Segers,P Simioni,D...
The risk of first venous thromboembolism during pregnancy and puerperium in double heterozygotes for factor V Leiden and prothrombin G20210A Background : The risk of venous thromboembolism (VTE) during pregnancy in double heterozygous carriers of factor (F) V Leiden and prothrombin G20210A is no....
Synonyms for Factor V Leiden mutation in Free Thesaurus. Antonyms for Factor V Leiden mutation. 34 synonyms for mutation: anomaly, variation, deviant, freak of nature, change, variation, evolution, transformation, modification, alteration, deviation...
Heterozygote status for FV Leiden was significantly more frequent in patients who had experienced their first episode of RVO before 60 years (p = 0.027). In conclusion, this study suggests a role of FV Leiden in the occurrence of RVO in patients younger than 60 years who exhibit fewer ...
increased 3- to 5-fold in Factor V Leiden heterozygotes.59,46 A Factor V Leiden allele is associated with a 6-fold increased risk for superficial vein thrombosis.60 Risk for a first VTE The relative risk for VTE is increased 3- to 8-fold in Factor V Leiden heterozygotes (Table 3). ...
BACKGROUND: Factor V Leiden mutation represents the most common genetic risk factor of venous thrombosis in Caucasian population. A common mutation in prothrombin gene, which is due to G-->A transition at position 20210, is also associated with elevated prothrombin concentration and thrombosis. Both...
The allelic frequency of FVL was 3.7% (6.9% heterozygotes, 0.3% homozygotes). Maternal FVL mutation was associated with significantly higher risks of pre-eclampsia (OR 1.63, 95%CI 1.15-2.30), pre-eclampsia at <37 weeks (OR 2.76, 1.34-5.70), low birth weight (OR 1.34, 95%CI 1.03-...
No matter whether the results were reported as homo- and heterozygotes or as mutated and healthy individuals, prothrombin was also found to be a risk factor for ischemic stroke. In the first case, the OR was 1.95, p < 0.05 (Figure 3), and in the second one, the OR = 5.16, p < ...
Under Hardy-Weinberg equilibrium, the relative frequency of normals:heterozygotes:homozygotes is p2:2pq:q2, where p is the allele frequency of the normal gene and q of the abnormal gene. As p2:2pq was 460/474:14/474, it follows that the allele frequency of factor V Leiden (q) is 0....