GENETEST REVIEW Genetics in Medicine Factor V Leiden thrombophilia Jody Lynn Kujovich, MD TABLE OF CONTENTS Pathogenic mechanisms and molecular basis ...2 Prevalence...2 Diagnosis...
Factor V Leiden (FVL) is the name of a specific gene mutation which leads to a hypercoagulability state with serious clinical consequences [5]. Less than two decades of its discovery, the pathophysiol- ogy, clinical consequences, and therapeutic management of the thrombophilic state associated to...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook factor VIII Thesaurus Medical Legal Financial Acronyms Encyclopedia Wikipedia Related to factor VIII:Factor VIII deficiency factor VIII n. A protein substance in blood plasma that is an essential part of the blood...
The Association of Factor V Leiden and Prothrombin Gene Mutation and Placenta-Mediated Pregnancy Complications: A Systematic Review and Meta-analysis of Pr... Background: Factor V Leiden (FVL) and prothrombin gene mutation (PGM) are common inherited thrombophilias. Retrospective studies variably ...
THE LEIDEN MUTATION OF THE FACTOR V GENE IN PREECLAMPSIA AND ECLAMPSIA 研究目的:以分子遺傳研究, 探討第五因子基因(Factor V gene)之來登突變 (Leiden mutation)與重度子癇前症/子癇症的相關.研究方法: 收集 105 位重度子癇前症/子癇症的... FM Chang 被引量: 0发表: 0年 The factor V Leiden ...
凝血因子Factor V是一种凝血过程中的蛋白因子,它位于内外源性凝血途径的交汇点,能够加速和促进凝血酶原的激活和凝血酶的生成。Factor V基因上的鸟嘌呤G突变为腺嘌呤A,造成第506上的谷氨酰胺被精氨酸替代,这样就形成了突变基因Factor V Leiden(FVL)。FVL会使凝血酶蛋白C(APC)的活性作用遭到抵抗,从而使血液的凝血功...
Our purpose was to describe a patient who developed combined central retinal vein occlusion (CRVO), cilioretinal artery occlusion, branch retinal artery occlusion (BRAO), and anterior ischaemic optic neuropathy (AION) followed by CRVO in the second eye because of the heterozygous factor V Leiden (...
Absence of the factor V Leiden mutation in Ethiopians 来自 Semantic Scholar 喜欢 0 阅读量: 13 作者:J Abdulkadir,Y Feleke,JP Berg,JA Falch,OR Odegaard 摘要: Abdulkadir J, Feleke Y, Berg JP, Falch JA, Odegaard OR.关键词:activated protein C resistance factor V mutation Ethiopian ...
The prevalence of the Leiden mutation was tested in 50 mothers of premature infants and in 56 mothers of intrauterine-growth-retarded neonates. The prevale... E Erhardt,J Stankovics,D Molnár,... - 《Biology of the Neonate》 被引量: 56发表: 2000年 Factor V Leiden and Prothrombin Gene 202...
219 However, other studies have concluded that factor V Leiden does not represent a risk factor for arterial thrombosis.220,221 Other allelic variants of the F5 gene have been described in regard to APC resistance and thrombosis. Two variants, F5 Arg306Thr (FV Cambridge) and F5 Arg306Gly (...