Exosome- loaded dendritic cells elicit tumor-specific CD8+ cytotoxic T cells in patients with glioma. J Neurooncol 104, 659-667.Bu N, Wu H, Sun B, et al. Exosome-loaded dendritic cells elicit tumor-specific CD8(+) cytotoxic T cells in patients with glioma. Journal of Neuro-Oncology . ...
The therapeutic benefits of many cell types involve paracrine mechanisms. Inspired by the paracrine functions of exosomes and the sustained degradation properties of microcapsules, here we report the therapeutic benefits of exosome-loaded degradable poly(lactic-co-glycolic acid) microcapsules with micrometri...
Exosome-loaded hydrogels as wound dressing The use of wound dressings is a common clinical practice to protect damaged tissue against the environment and bacterial infection. An ideal dressing also facilitates wound closure and actively supports the healing process by providing an optimal wound environmen...
In this study, we demonstrate that tumor-derived exosome-loaded dendritic cells can elicit a specific CD8 + cytotoxic T-lymphocyte (CTL) response against autologous tumor cells in patients with malignant glioma. Exosomes were purified by ultrafiltration centrifugation and sucrose gradient ultracentrifugation...
Therefore, the promising exosome-loaded hydrogels can be designed for craniofacial bone regeneration. This review lists the packaging techniques for exosomes and hydrogel and discusses the development of a biocompatible hydrogel system and its potential for exosome continuous delivery for craniofacial bone ...
Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation M. Rezaa Mohammadi, Samuel Mathew Rodriguez, Jennifer Cam Luong, Shiri Li, Rui Cao, Hamad Alshetaiwi, Hien Lau, Hayk Davtyan, Mathew Blurton Jones, ...
M2 microglia-derived exosome-loaded electroconductive hydrogel for enhancing neurological recovery after spinal cord injury Pengfei Guan, Lei Fan, Zhaobo Zhu, Qinfeng Yang, Xinchang Kang, Junji Li, Zuyu Zhang, Shencai Liu, Can Liu, Xuelian Wang, Jing Xu, Kun Wang & Yongjian ...
glucose control. Reportedly, metformin-loaded reactive release systems accelerate the healing of diabetic foot wounds [26]. The drug–bioactive agent combination synergistically promotes wound healing [27,28] but it remains unclarified whether the combinatorial effect of metformin and exosome is additive...
The team hypothesized that these exosomes, when loaded onto a gelatin sponge, a common hemostatic material, would enhance hemostasis and acceleratewound healing.Their study, titled "Enhanced wound healing and hemostasis withexosome-loaded gelatin sponges from human umbilical cord mesenchymal stem cells,"...
Human CAP cells represent a novel source for functional, miRNA-loaded exosome production 来自 学术范 喜欢 0 阅读量: 12 作者:N Zeh,H Schneider,S Mathias,N Raab,K Otte 摘要: Exosomes represent a promising delivery tool for nucleic acid-based pharmaceuticals. They are highly suitable for ...