定制探针(1个月) 探针组分: EWSR1/ERG双色探针 注册证号: 不作为医疗器械管理 应用癌种: 软组织肿瘤 探针设计 ERG基因(21q22)标记为橘红色,总长度为852kb; EWSR1基因(22q12)标记为绿色,长度为1.3Mb; 临床意义 软组织肿瘤 参考文献 Genes Chromosomes Cancer. 2016 Apr;55(4):340-9. ...
Herein, we aimed at validating the specificity of both markers in a far larger and independent cohort of EwS (including EWSR1-ERG-positive cases) and differential diagnoses. Furthermore, we evaluated their intra-tumoral expression heterogeneity. Thus, we stained tissue microarrays from 133 ...
Ewing sarcomas (ES) are rare small round cell sarcomas often affecting children and characterized by gene fusions involving one member of the FET family of genes (usually EWSR1) and a member of the ETS family of transcription factors (usually FLI1 or ERG). The detection of EWSR1 ...