The advent of high-throughput epigenome mapping technologies has ushered in a new era of multiomics where powerful tools can now delineate and record different layers of genomic output. Integrating various components of the epigenome from these multiomics measurements allows the interrogation of cellular...
Next-Generation Sequencing in Cancer Epigenomics and Potential Clinical Applications The arrival of next-generation sequencing (NGS) technologies has greatly empowered research in many fields, including the study of epigenetics in normal bi... KN Hong,DH Roukos,B Iacopetta,... - Springer New York...
Dailey L. High throughput technologies for the functional discovery of mammalian enhancers: new approaches for understanding transcriptional regulatory network dynamics. Genomics. 2015;106(3):151–8. Article CAS Google Scholar van der Velde A, Fan K, Tsuji J, Moore JE, Purcaro MJ, Pratt HE, ...
three major crops, and discuss the prospects and challenges for new epigenetics-mediated breeding technologies in crop improvement.#In this review, we summarize and analyze recent epigenomic advances in three major crops epigenomics and discuss possibilities and challenges for future research in the ...
作者: CS Cho 摘要: Epigenomics is the comprehensive analyses of the entire epigenomeusing high-throughput technologies, including physical modifications, associations, and conformations of genomic DNA sequences. The... DOI: 10.1007/978-3-642-27841-9_1950-5 年份: 2017 收藏...
further enabling detection of DNA modifications, including methylation,13 as well as epigenetic RNA modifiers of gene expression (e.g., microRNAs [miRNAs]).14, 15 Additionally, advancements in micro-fluidics resulted in next-generation sequencing technologies and applications16, 17 commonly used today...
flow cytometry and has 13 years of research experience spanning both academia and biotech. At BD Biosciences, she is a member of the Applied Research & Technology team and works on novel applications utilizing the unique capabilities of BD flow cytometers and single-cell multiomic technologies. ...
our study encompasses an up-to-date range of commonly used whole methylome assays as well as emerging methods such as enzymatic methylation and native 5mC calling from long-read technologies and provides data across 7 different reference material cell lines, providing a comprehensive examination of ...
With the advent of high-throughput next-generation sequencing technologies, over the past decade, we have witnessed an explosion in the number of assays to characterize the epigenome and interrogate the chromatin state, genome wide. Assays to measure chromatin accessibility (DNase-seq, ATAC-seq, ...
We provide many innovative technologies to speed up your whole-genome and targeted sequencing workflow for somatic variant and CNV discovery, including our patented SMARTer ThruPLEX technology. All of our SMARTer ThruPLEX kits are designed to reduce user error, sample loss, and contamination with a ...