Most of the current studies investigating the mechanisms in the regulation of brown fat thermogenesis focus on cellular signaling pathways; much less is known about the epigenetic mechanisms in this process. We have recently discovered several epigenetic pathways involved in adipocyte development and brown...
e, Representative retinal cross-section B-scan images. White box indicates the location of the high magnification scans in f (retinal layers: GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer and choroid). Videos of complete retinal cross-section B-scan images of ...
41]. Increased progesterone signalling during the post-ovulatory phase leads to increased proliferation and thus accelerated mitotic ageing in the mammary epithelium stem cell pool. A biomarker with a fixed and stable signal such as a DNA-based marker would be strongly preferred to evaluate replicativ...
A data-dependent procedure that alternated between one MS scan followed by 20 MS/MS scans with 15.0 s dynamic exclusion. Automatic gain control was set at 5E4. The resulting MS/MS data were processed using Mascot Daemon (version 2.3.0). Tandem mass spectra were searched against 2019-...