Epigenetics in CancerWhy subscribe and readWhy submit
The last few years has seen growing interest in the function of epigenetics in cancer initiation and progression. A growing volume of work now underpins our understanding of the role of these non-genetic modifications in the molecular biology of disease initiation and metastatic spread, and how ...
The emergence of nanotechnology applied to medicine has revolutionized the treatment of human cancer. As in the case of classic drugs for the treatment of cancer, epigenetic drugs have evolved in terms of their specificity and efficiency, especially because of the possibility of using more effective ...
Epigenetics in cancer. Epigenetic mechanisms are essential for normal development and maintenance of tissue-specific gene expression patterns in mammals. Disruption of epigenetic... M Esteller - 《Carcinogenesis》 被引量: 6196发表: 2010年 Epigenetics in cancer. Epigenetic mechanisms are essential for nor...
Epigenetics in cancer. N Engl J Med, 2008; 358, 1148-59.Sharma S, Kelly TK, Jones PA. Epigenetics in cancer. Carcinogenesis. 2010;31:27-36.Sharma S, Kelly TK, Jones PA. Epigenetics in cancer. Carcino- genesis 2010; 31(1): 27-36....
has been evaluated for use as a screening strategy. One of the largest studies to examine this combination was the PLCO Cancer Screening trial, which enrolled 78,216 women 55–74 years of age [18]. Ovarian cancer was diagnosed in 212 women (5.7 per 10,000 person-years) in the screening...
Cancer Treat Res 1995;72:91-110.Verma M, Srivastava S: Epigenetics in cancer: implications for early detection and prevention. Lancet Oncol 2002, 3(12... S Srivastava,BS Kramer - Springer US 被引量: 311发表: 1994年 Introduction: epigenetics and cancer. implication for better understanding of...
Epigenetics breaks into the clinical practice of cancer表观遗传学闯入癌症的临床实践 souyou 科研新闻,不定期更新!何塞普-卡雷拉斯白血病研究所的研究人员马内尔-埃斯特勒博士和维罗尼卡-达瓦罗斯博士在一篇新文章中描述了表观遗传学对癌症治疗的影响,以及它如何成为改善早期检测、预测疾病进展并成为新治疗方法的目标...
Epigenetic dysregulation is a common feature of a myriad of human diseases, particularly cancer. Defining the epigenetic defects associated with malignant tumors has become a focus of cancer research resulting in the gradual elucidation of cancer cell ep
Alterations in the epigenome and metabolism both affect molecular rewiring in cancer cells and facilitate cancer development and progression. However, recent evidence suggests the existence of important bidirectional regulatory mechanisms between metabolic remodelling and the epigenome (specifically methylation and...