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DNA Methylation Alterations in Multiple Myeloma as a Model for Epigenetic Changes in Cancer WIREs Systems Biology and Medicine Amy Sharma, Christoph J. Heuck, Melissa J. Fazzari, Jayesh Mehta, Seema Singhal, John M. Greally and Amit Verma ...
Sharma S, Kelly TK, and Jones PA (2009) Epigenetics in cancer. Carcinogenesis 31(1): 27-36. Shoemaker AR, Gould KA, Luongo C, Moser AR, Dove WF (1997) Studies of neoplasia in the Min mouse. Biochim. Biophys. Acta, 1332: F25-F48....
The emergence of nanotechnology applied to medicine has revolutionized the treatment of human cancer. As in the case of classic drugs for the treatment of cancer, epigenetic drugs have evolved in terms of their specificity and efficiency, especially because of the possibility of using more effective ...
The last few years has seen growing interest in the function of epigenetics in cancer initiation and progression. A growing volume of work now underpins our understanding of the role of these non-genetic modifications in the molecular biology of disease initiation and metastatic spread, and how ...
Epigenetics in prostate cancer: biologic and clinical relevance. Epigenetic alterations are common in prostate cancer. Along with their role in tumourigenesis, gene promoter hypermethylation, histone marks, altered expre... C Jerónimo,PJ Bastian,A Bjartell,... - 《European Urology》 被引量: 260发...
Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes Enhancer of zeste homolog 2 (EZH2) has been implicated as a driver of disease progression and resistance to hormonal therapies. Here, the authors focus on EZH2 in two subtypes of advanced prostate can...
The emergence of nanotechnology applied to medicine has revolutionized the treatment of human cancer. As in the case of classic drugs for the treatment of cancer, epigenetic drugs have evolved in terms of their specificity and efficiency, especially beca
Compelling evidence have demonstrated that bulk tumors can arise from a unique subset of cells commonly termed “cancer stem cells” that has been proposed to be a strong driving force of tumorigenesis and a key mechanism of therapeutic resistance. Recen
Epigenetics in cancer 作者:Sharma Shikhar; Kelly Theresa K; Jones Peter A* 来源:Carcinogenesis, 2010, 31(1): 27-36. DOI:10.1093/carcin/bgp220 摘要 Epigenetic mechanisms are essential for normal development and maintenance of tissue-specific gene expression patterns in mammals. Disruption of epigene...