Eosinophils are involved in a variety of allergic and other inflammatory conditions such as asthma, pulmonary fibrosis, lung cancer, food allergy, inflammatory bowels disease, and are often associated with tissue destruction. We have examined if eosinophils migrate, degranulate and release growth ...
Eosinophils are the specific kind of white blood cell, involved in the pathophysiology of several inflammatory and malignant disorders as well as innate immunity. They contribute to the innate immune response by secreting highly cytotoxic proteins from their secretory granules in opposition to bacteria, ...
As innate immune cells, eosinophils are involved in host defense. They express several pattern recognition receptors, including toll-like receptors (TLR), nucleotide-binding oligomerization domain-like receptors (NLRs), G protein-coupled, Fc, chemokine, adhesion, and cytokine receptors [16,17]. Recep...
APRIL-producing eosinophils are involved in gastric MALT lymphomagenesis induced by Helicobacter sp infectionThe roles of the inflammatory response and production of a proliferation-inducing ligand (APRIL) cytokine in gastric mucosa-associated lymphoid tissue (MALT) lymphomagenesis induced by Helicobacter ...
REVIEW nature publishing group See REVIEW page 444 Eosinophils in mucosal immune responses J Travers1 and ME Rothenberg1 Eosinophils, multifunctional cells that contribute to both innate and adaptive immunity, are involved in the initiation, propagation, and resolution of immune responses, including ...
Neutrophils but not eosinophils are involved in growth suppression of IL-4-secreting tumors. 来自 Semantic Scholar 喜欢 0 阅读量: 57 作者:GT Noffz,Z Qin,M Kopf,T Blankenstein 摘要: Local expression of IL-4 by gene-modified tumor cells increases their immunogenicity by inducing an inflammatory ...
As effector granulocytes, they contribute to the inflammation in asthma by releasing cytotoxic granule proteins, lipid mediators, oxygen free radicals, and cytokines. By these actions, eosinophils are involved in the initiation and perpetuation of airway inflammation in asthma....
We now know that eosinophils are involved in many processes essential to our health.1,2 As a type of white blood cell, eosinophils contribute to our immune defence against infections.1,2 But eosinophils are even more hard working than we thought, with a role in homeostasis (maintaining balance...
Under pathological circumstances, eosinophils are involved in host protection against parasites and participate in allergy and inflammation. Discussion:Mostly, in asthma, eosinophils provoke airway damage via the release of granule contents and IL-13 with mucus hypersecretion and differentiation of goblet ...
Background/Aims: Although eosinophils are considered to play an important role in the pathogenesis of various parasitic, allergic and autoimmune digestive diseases, their role in fulminant hepatic failure (FHF) is unknown. Our contribution was to identify and quantify eosinophils and cytokine levels [...