Eosinophils function is related to destructive activity mediated by the toxic effects of the granule proteins and soluble mediators derived by the cells. Vitamin D, as a potent immunomodulator, has an unknown role in the eosinophil-induced asthmatic response. It was previously reported that in vivo...
Eosinophils Regulate Peripheral B Cell Numbers in Both Mice and Humans. Wong TW, Doyle AD, Lee JJ and Jelinek DF: Eosinophils regulate peripheral B cell numbers in both mice and humans. J Immunol 192:... Wong,W Tina,Doyle,... - 《Journal of Immunology》 被引量: 36发表: 2014年 T cel...
Segmental allergen challenge alters multimeric structure and function of surfactant protein D in humans. Rationale: Surfactant protein D (SP-D), a 43-kD collectin, is synthesized and secreted by airway epithelia as a dodecamer formed by assembly of four trimer... EN Atochina-Vasserman,C Winkler...
In humans, the number and the activity of eosinophils correlates with bone mass in healthy participants and rheumatoid arthritis patients. Taken together, experimental and human data indicate a regulatory function of eosinophils on bone.Similar content being viewed by others Ncf1 affects osteoclast ...
The relationship of eosinophilia with smoking habits and with baseline lung function measurements has been studied in a working population of 912 men in the Paris area. Absolute numbers of eosinophils were related significantly to a history of asthma and eczema in childhood as well as to current ...
These tools have been invaluable for shaping our current views on eosinophil function and for generating new hypotheses for future examination. The unique biology of the eosinophil Relatively few mature eosinophils are found in the peripheral blood of healthy humans (less than 400 per mm3), but ...
function, as in vivo murine studies have demonstrated that eosinophils prime IgM production during primary immune responses to T cell-dependent antigens by secreting IL-4 that induces B-cell differentiation and thereby generates IgM-producing plasma cells.46 In addition, eosinophils promote B-cell ...
The effector function is thought to be related to the release of highly cytotoxic, granule-associated cationic proteins following stimulation of eosinophils. In spite of strong arguments in favor of either end of this spectrum, the evidence remains circumstantial; the precise role of this cell in ...
Neurohormonal and inflammatory hyper-responsiveness to acute mental stress in depression Depression is associated with dysregulated hypothalamic–pituitary–adrenal (HPA) axis function, overactivity of the sympathoadrenal system, and increased ... AA Weinstein,PA Deuster,JL Francis,... - 《Biological ...
Mast cell polymorphisms Although mast cells are widely distributed in the body, their functions are poorly known. The elucidation of mast cell function is complicated by growing e... D Befus,H Fujimaki,TDG Lee,... - 《Digestive Diseases & Sciences》 被引量: 48发表: 1988年 加载更多来源...