SARAHROBERTSON,SCOTTPENZAK, inPrinciples of Clinical Pharmacology (Second Edition), 2007 Enzyme Inhibition Inhibition of enzyme activity is a common mechanism of clinically significant metabolic drug interactions.Enzyme inhibitiondecreases the rate of drug metabolism, thereby increasing the amount of drug in...
The effects of enzyme induction and enzyme inhibition on labetalol pharma- cokinetics. Br J Clin Pharmacol 1984;18:393-400.Daneshmend TK, Roberts CJe. The effects of enzyme induction and enzyme inhibition on labetalol pharmacokinetics. British Journal of Clinical Pharmacology 18: 393-400, 1984...
Journal of Enzyme Inhibition and Medicinal Chemistry aims to provide an international and interdisciplinary platform for the latest findings in enzyme inhibition research. The journal’s focus includes current developments in: Enzymology; Cell biology; Chemical biology; Microbiology; Physiology; Pharmacology ...
今天介绍的是一本生物化学与药物化学领域的期刊Journal of enzyme inhibition and medicinal chemistry,创办于2002年,植根英国,目前由Informa Healthcare出版或管理。 ISSN:1475-6366 01 影响因子 该期刊的影响因子在2017小跌后,一直一路上涨,2020年影响因子已破5分,为5.051。 02 分区 根据最新JCR分区,该杂志在PHARMA...
enzyme inhibitionenzyme inductiondrug–drug interactionactive metabolite1. Antipsychotic drugs are extensively metabolised by cytochrome P450 (CYP) enzymes. 2. ... J Fang,JW Gorrod - 《Cellular & Molecular Neurobiology》 被引量: 93发表: 1999年 Evaluation of drug–drug interactions in drug metabolism...
《酶抑制与药物化学杂志》(Journal Of Enzyme Inhibition And Medicinal Chemistry)是一本以医学-生化与分子生物学综合研究为特色的国际期刊。该刊由Informa Healthcare出版商创刊于2002年,刊期Bimonthly。该刊已被国际重要权威数据库SCIE收录。期刊聚焦医学-生化与分子生物学领域的重点研究和前沿进展,及时刊载和报道该领域...
Pharmacology leading to drug design; Molecular recognition processes; Distribution and metabolism of biologically active compounds. 中文简介 《酶抑制与药物化学杂志》发表关于酶抑制剂、抑制过程和激动剂/拮抗剂受体相互作用在药物和抗癌剂开发中的开放获取研究。
(1989), The effect of liver enzyme inhibition by cimetidine and enzyme induction by phenobarbitone on the pharmacokinetics of paroxetine. Acta Psychiatrica Scandinavica, 80: 95–98. doi: 10.1111/j.1600-0447.1989.tb07184.x Author Information 1 Beecham-Wülfing Clinical Pharmacology Research Institute,...
(Pharmacology) any one of a class of drugs, including captopril, enalapril, and ramipril, that cause the arteries to widen by preventing the synthesis of angiotensin: used to treat high blood pressure and heart failure [C20: from a(ngiotensin-)c(onverting) e(nzyme) inhibitor] Collins Engli...
G Yixuan,GL Firestone,LF Bjeldanes - 《Molecular Pharmacology》 被引量: 80发表: 2006年 Relevance of benzyloxy group in 2-indolyl methylamines in the selective MAO-B inhibition Previous studies with indolyl derivatives as monoamine oxidase (MAO) inhibitors have shown the relevance of the indole ...