研究结果反映了内毒素对肠黏膜屏障作用的调控机制,为深入了解肠黏膜免疫屏障功能提供了思路。相关内容发表在 Frontiers in Immunology 期刊题为“Endotoxins Induced ECM-Receptor Interaction Pathway Signal Effect on the Function of MUC2 in Caco2/HT29 Co-Culture Cells”。 HT-29细胞常用作体外杯状细胞模型,可产生...
而后，GO以及KEGG通路富集分析发现细胞外基质（ECM）受体互作通路（ECM-receptor interaction pathway）显著富集（图2）。并且，整合素家族基因（integrins）作为一种ECM受体，在耐药细胞系中的表达显著提高，说明该基因参与的通路被异常激活。然而，这些整合素是如何发挥功能的呢？研究人员首先聚焦到整合素下游激酶Src和Fak。...
Mechanistic analyses indicated that the ECM-receptor interaction pathway was remarkably activated by SNHG16. Conclusions: SNHG16 might be a promising biomarker for predicting tumor recurrence in HCC patients after surgery and a potential therapeutic target for HCC.Qi-Jun ZhangDa-Zhi LiBing-Yi Lin...
Ontogenetic Development and Distribution of Antibody Transport and Fc Receptor mRNA Expression in Rat Intestine The intestine of the suckling rat has the uniquecapacity of absorbing immunoglobulins from maternalmilk. We investigated intestinal Fc receptor mRNAexpress... MG Martin,SV Wu,JH Walsh - 《...
1月16日,浙江大学医学院附属第一医院郑树森院士,杨哲,耿磊等组成的团队,在期刊 Hepatobiliary & Pancreatic Diseases International 发表题为 SNHG16 promotes hepatocellular carcinoma development via activating ECM receptor interaction pathway 的论文。 编辑于 2024-10-31 14:04・IP 属地吉林 ...
The extracellular matrix–receptor (ECM-receptor) interaction pathway was the most enriched pathway: all genes in this pathway were DEGs, including the THBS family, collagen and fibronectin. These DEGs and the ECM-receptor interaction pathway may perform important roles in breast cancer. Conclusion ...
The discovery of focal adhension, ECM-receptor interaction and iron uptake pathway might contribute to the understanding of the mechanism and effective therapies for osteoporosis. However, further research on the relation between EMC-receptor interaction and osteoporosis were in need. 展开 ...
Hedgehog signaling pathway PI3K-Akt signaling pathway AMPK signaling pathway View more pathways>> All All Primary antibodies Secondary antibodies Peptides ECM-receptor interaction The extracellular matrix (ECM) consists of a complex mixture of structural and functional macromolecules and serves an important...
Many DEGs from the adipose tissues were enriched in the various GO terms of developmental process and KEGG pathway analysis showed that the ECM-receptor interaction was one of commonly enriched pathways in all of the 3 adipose tissues and also functioned as a sub-pathway of other enriched ...
ECM receptor pathway analysis; integrin transcripts.Yurika, TachibanaToshihiro, SakuraiHanako, BaiKunio, ShiotaYasuo, NamboKentaro, NagaokaKazuhiko, Imakawa