Because an in-depth understanding of cell interactions with the ECM will be important for developing novel approaches to disease therapy, we conclude with a discussion of the implications of these findings for the rational design of bioengineered scaffolds in regenerative medicine strategies, as well ...
1.FRANCESCO ROSSO,* ANTONIO GIORDANO, From Cell–ECM Interactions to Tissue Engineering,JOURNAL OF CELLULAR PHYSIOLOGY 199:174–180 (2004) 2.Adams JC, Watt FM. 1993. Regulation of the development and differentiation by extracellular matrix. Development 117:1183–1198. 3.Aplin AE, Hogan BP, Tome...
They orchestrate cell-cell and cell-matrix adhesive interactions from embryonic development to mature tissue function. In this review, we emphasize the signaling molecule effect and the biomechanics effect of cartilage ECM on chondrogenesis. 展开 ...
Engineering spheroids potentiating cell-cell and cell-ECM interactions by self-assembly of stem cell microlayer - ScienceDirect Engineering spheroids potentiating cell-cell and cell-ECM interactions by self-assembly of stem cell microlayer. Biomaterials 2018, 165, 105-120. [CrossRef... Yu Bin Lee ...
The extracellular matrix (ECM) consists of a plex mixture of structural and functional macromolecules and serves an important role in tissue and organ morphogenesis and in the maintenance of cell and tissue structure and function. Specific interactions between cells and the ECM are mediated by transme...
JeongKwangheeBIOMATERIALS -GUILDFORD-Lee, Y.; Kim, E.; Byun, H.; Chang, H.; Jeong, K.; Aman, Z.; Choi, Y.; Park, J.; Shin, H. Engineering spheroids potentiating cell-cell and cell-ECM interactions by self-assembly of stem cell microlayer. Biomaterials 2018, 165, 105-120. [...
Meanwhile, the protein-protein interaction (PPI) network was constructed to predict the interactions of the DEGs using STRING (Search Tool for the Retrieval of Interacting Genes) database. Function enrichment analysis was then performed with GSEA (Gene Set Enrichment Analysis) method to reveal the ...
Cell Death & DifferentiationBrafman DA, Phung C, Kumar N, Willert K. Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions. Cell Death Differ. 2013; 20 (3):369–381. doi: 10.1038/cdd.2012.138. [ Cross Ref ]...
Equally important, the viscoelasticity of bone ECM can also affect cell-ECM interactions, thereby regulating cell behaviors and fate (Chaudhuri, Cooper-White, Janmey, Mooney, & Shenoy, 2020; Darnell et al., 2017). Viscoelastic signals are transmitted into cells through actin, which then promotes...
Of special interest is the cell-based, CPM, a multi-particle lattice description, that is capable of modeling cell–cell and cell–ECM interactions37. In CPM, physical properties of bio- logical entities (e.g., cell, ECM fibre, etc.) can be taken into account by modeling them as multi...