ECM的张拉整体结构 图片来源:Tensegrity I : Cell structure and hierarchical systems biology 过去二十年的科学研究已经证实:细胞外基质(ECM)不仅仅只是为组织和机体提供力学支持和物理强度,ECM的刚度和弹性还会广泛影响细胞的所有生物学行为过程,包...
We provide an overview of recent progress in the development and application of state-of-the-art 3D ECM biomaterials including cell-derived ECM, ECM scaffolds, Matrigel, and ECM hydrogels for studies of TM and SC cell (patho)biology. Such bioengineered platforms enable accurate and reliable ...
This review discusses recent insights into the regulatory functions of the ECM and their role in disease, focusing on cancer as a paradigm.doi:10.1016/S0962-8924(98)01362-2Lukashev MEWerb ZTrends Cell BiolTrends in Cell Biology
16 Kim J, et al. Human organoids: model systems for human biology and medicine. Nat Rev Mol Cell Biol. 2020 Oct;21(10):571-584. 17 Ramadan R, et al. The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.Biol Open. 2022 De...
Integrins are a large family of molecules that are central regulators in multicellular biology. They orchestrate cell-cell and cell-matrix adhesive interactions from embryonic development to mature tissue function. In this review, we emphasize the signaling molecule effect and the biomechanics effect of...
31. Lau LF, Lam SCT. The CCN family of angiogenic regulators: the integrin connection. Exp Cell Res. 1999;248:44–57. 32. Leask A, Abraham DJ. The role of connective tissue growth factor, a multifunctional matricellula...
原名:ECM deposition is driven by caveolin-1–dependent regulation of exosomal biogenesisand cargo sorting译名:依赖caveolin-1的外泌体生物发生和货物分选的调节所驱动的ECM沉积期刊:Journalof Cell BiologyIF:8.811发表时间:2020.10通讯作者:Inmaculada Navarro-Lérida,MiguelÁngel del Pozo通讯作者单位:西班牙马德里...
During collective cell migration, cell–cell and cell–extracellular matrix (ECM) adhesions must be integrat... C Collins,WJ Nelson - 《Current Opinion in Cell Biology》 被引量: 69发表: 2015年 The Urokinase Plasminogen Activator Receptor in the Regulation of the Actin Cytoskeleton and Cell ...
TissueSpec™使用方法:https://inmatrico.com/wp-content/uploads/2022/10/MTSXX101-IFU.pdf 更多技术资料及Protocal欢迎向我们咨询。 ◆数据示例 ① TissueSpec™ 骨ECM水凝胶:猪骨来源 ■ 使用示例:促进骨芽细胞的分化 -TissueSpec™ 骨 ECM水凝胶支持成骨细胞表型培养- 将原代人成骨细胞在TissueSpec™...
- 《Faseb Journal Official Publication of the Federation of American Societies for Experimental Biology》 被引量: 36发表: 2015年 Traction Stresses and Translational Distortion of the Nucleus During Fibroblast Migration on a Physiologically Relevant ECM Mimic Cellular traction forces, resulting in cell-...