Dual specificity phosphatase-4 (DUSP4) It is a keyenzymein the DUSP family, which are involved in thedephosphorylationand inactivation of MAPKs. Decreased expression or loss of function of DUSP4 has been associated with the progression of certain cancers (Balko et al., 2013; Saigusa...
Dual-specificity phosphatase 1-null mice exhibit spontaneous osteolytic disease and enhanced inflammatory osteolysis in experimental arthritis. Arthritis Rheum. 2012; 64: 2201-2210. doi: 10.1002/art.34403 PMID: 22275313Vattakuzhi, Y., S. M. Abraham, A. Freidin, A. R. Clark, and N. J. ...
上海玉博生物科技有限公司 主要致力于“VHR Dual-specificity Phosphatase (human) (recombinant) BML-SE333-0050”的生产销售。多年的“VHR Dual-specificity Phosphatase (human) (recombinant) BML-SE333-0050”生产与销售的经验,与各行业新老用户建立了稳定的合作关系
The three main MAPKs, extracellular signal-regulated kinase (ERK), p38 and c-Jun N-terminal kinase (JNK), have been intimately associated with immune responses, whereby the magnitude and duration of their activity determines the type of immune cell response, according to the type of stimuli the...
英文名称: Dual Specificity Phosphatase 23 Human Recombinant 总访问: 280 国产/进口: 进口 半年访问: 18 产地/品牌: prospec 产品类别: 细胞生物学试剂 规格: ENZ-195 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询 ...
Dual-specificity phosphatase (DUSP) genetic variants predict pulmonary hypertension in patients with bronchopulmonary dysplasiaPulmonary hypertension (PH) in patients with bronchopulmonary dysplasia (BPD) results from vasoconstriction and/or vascular remodeling, which can be regulated by mitogen-activated ...
Dual-specificity phosphatase 14 (DUSP14; also known as MKP6) is classified as a MAPK phosphatase. The in vivo functions of DUSP14 remain unclear. Thus, we generated DUSP14-deficient mice and characterized the roles of DUSP14 in T cell activation and immune responses. DUSP14 deficiency in...
The mechanical remodeling of tumor microenvironment is critical for non-small cell lung cancer (NSCLC) progression. Dual-specificity phosphatase 23 (DUSP23) has been previously identified as a mechano-responsive gene, but its role in NSCLC progression remains unknown.We aim to elucidate the clinical...
In response to injury, vascular smooth muscle cells (VSMCs) of the arterial wall dedifferentiate into a proliferative and migratory phenotype, leading to intimal hyperplasia. The ERK1/2 pathway participates in cellular proliferation and migration, while dual-specificity phosphatase 6 (DUSP6, also na...
Our study demonstrated that the expression of dual‐specificity phosphatase 26 (Dusp26), a member of the Dusp protein family, was decreased in the liver tissue of mice with hepatic steatosis and genetically obese (ob/ob) mice. In our study, hepatic steatosis, inflammatory responses, and ...