DGIdb数据库(Drug-Gene Interaction database),是一个药物-基因相互作用数据库,提供了基因与其已知或潜在药物关联信息,目前已经更新到4.0版本。里面的基因主要是癌基因,但是也有一些其他疾病(例如阿尔兹海默病、心脏病、糖尿病等)的相关基因。DGIdb一共有超过14000种药物-基因的相互作用,涉及2600个基因和6300中靶向这些...
Organ Impairment-Drug-Drug Interaction DatabaseC. K. YeungK. YoshidaM. KusamaH. ZhangI. RagueneauMajlessiS. ArgonL. LiP. ChangC. D. LeP. Zhao
Drug-drug interaction (DDI) can trigger many adverse effects in patients and has emerged as a threat to medicine and public health. Despite the continuous information accumulation of clinically significant DDIs, there are few open-access knowledge systems dedicated to the curation of DDI associations...
ddiinterpretable-deep-learningmulti-view-learningdrug-drug-interactiondrugbank-database UpdatedJul 30, 2023 Python A Virtual Reality Experience - Project to examine the productivity and usefulness of Virtual Reality as a tool for education virtual-reality-experiencesvirtual-realityeducational-gameeducational-...
Drug-herb interaction: database of medicinal plants of the caribbean, their indications, toxicities and possible interactions with conventional medication / La Interacción entre medicamentos y hierbas: base de datos de las plantas medicinales en el caribe, sus indicaciones, toxicidades y posibles ...
et al. Integration of the Drug–Gene Interaction Database (DGIdb) with open crowdsource efforts. Preprint at biorxiv https://doi.org/10.1101/2020.09.18.301721 (2020). Article Google Scholar Manolio, T. A. et al. Finding the missing heritability of complex diseases. Nature 461, 747–753 (...
Drug Gene Interaction Database (DGIdb) web resource43 was used to retrieve FDA-approved drugs that interact with 25 genes including the top ranked nodes of the core network (Table 2) and the identified TFs. We found 10 out of the 25 genes (7 upregulated DEGs and 3 TFs) have 64 intera...
The Drug–Gene Interaction Database (DGIdb,www.dgidb.org) is a web resource that consolidates disparate data sources describing drug–gene interactions and gene druggability. It provides an intuitive graphical user interface and a docume... AH Wagner,AC Coffman,BJ Ainscough,... - 《Nucleic Aci...
The simultaneous administration of multiple drugs increases the probability of interaction among them, as one drug may affect the activities of others. This interaction among drugs may have a positive or negative impact on the therapeutic outcomes. Thus, identification of unknown drug-drug interactions...
The method integrates a reference standard database of known DDIs with drug similarity information extracted from different sources, such as 2D and 3D molecular structure, interaction profile, target and side-effect similarities. The method is interpretable in that it generates drug interaction ...