Unlike in prostate cancer, in the neovasculature the PSMA-RL / PSMA-receptor complex might not be internalized. One article reported on internalization in endothelial cells, however, they tested monoclonal antibodies and nanoparticles [12]. We have not found any other article reporting on internaliza...
Pure Red Cell Aplasia Associated with Plasma Cell Myeloma: Does Monoclonal Protein Inhibit Erythropoiesis? - ScienceDirect642 Pure red cell aplasia (PRCA) is a rare hematologic disorder characterized by selective inhibition of red cell precursors in the bone marrow. The pathogenesis of PRCA is ...
Mouse monoclonal anti-FLAG M1, biotinylated monoclonal anti-FLAG M2, and mouse anti-β–actin monoclonal antibodies were purchased from Sigma (Saint-Quentin Fallavier, France), and the phycoerythrin (PE)-conjugated goat antimouse IgG2b antibody was obtained from SBA (Birmingham, AL, USA). Cell ...
OPEN Cancer Gene Therapy (2016) 23, 355–364 www.nature.com/cgt ORIGINAL ARTICLE Expression of the fusogenic p14 FAST protein from a replication-defective adenovirus vector does not provide a therapeutic benefit in an immunocompetent mouse model of cancer CM Wong1,2,3, LA Nash1,2,3, J ...
Protein kinases (PKs) have emerged as one of the most intensively investigated drug targets in current pharmacological research, with indications ranging from oncology to neurodegeneration. Tau protein hyperphosphorylation was the first pathological post
Too big to fail in banking: What does it mean? Interest in too big to fail (TBTF) resolutions of insolvent large complex financial firms has intensified in recent years. TBTF resolutions protect some in... Kaufman,G George - 《Journal of Financial Stability》...
Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. Blood. 1991;78:155–62. Google Scholar Tormin A, Li O, Brune JC, et al. CD146 expression on primary nonhematopoietic bone marrow stem cells is correlated with in situ localization. Blood...
(HCC) is a major health problem worldwide and is the third most common cause of cancer- related death.1 Hepatitis B virus and hepatitis C virus infection are the most important HCC risk factors; chronic liver injury is typically associated with increased remodeling activity, a mas- sive ...
The progeny were then immunized with human GDF8 protein. The resulting antibody is a fully human IgG4 monoclonal specific for GDF8 with no cross-reactivity to GDF11. An IgG4 isotype antibody was used as control for all antibody experiments. Activin A, B, AB, AC, GDF8 and GDF11 protein...
(B) The ability of MigR1 cells to bind fibronectin was determined by leaving cells untreated (No treatment) or treating cells with a control Rat immunoglobulin G (IgG) antibody, a monoclonal antibody directed against the fibronectin-binding region of α4β1 (anti-α4), a monoclonal antibody ...