The monoclonal antibodies are valuable for detecting the corresponding proteins or polypeptides in mixtures which contain them. When the antibodies are immobilised on an insoluble support, they can be used for purifying the corresponding polypeptides from mixtures which contain them. CHASSAGNE, JACQUES...
For immunofluorescence staining or Western analysis, the following antibodies were used: Rabbit anti-LC3A/B (D3U4C) monoclonal antibodies (CST, #12741, Western 1:1000, immunofluorescence 1:200); Rabbit anti-LAMP1 (D2D11) monoclonal antibodies (CST, #9091, immunofluorescence 1:200); Rabbit anti...
We screened 26 gonococcal proteins discovered by an artificial intelligence-driven platform called Efficacy Discriminative Educated Network (EDEN) trained to identify novel, protective vaccine antigens against pathogenic bacteria for efficacy in the mouse vaginal colonization model of gonorrhea. Combinations...
On a subset of proteins this mannose is then extended by the sequential action of two enzyme complexes (mannan polymerases M-Pol I and M-Pol II) to form the long mannan backbone. The branches are then made by the sequential action of Mnn2p, Mnn5p, and Mnn1p. Phosphomannose and β-...
Based on QUANTISEQ analysis, a significant positive correlation between NOX1 expression and M2-type, but not M1-type macrophage infiltration was observed in cervical cancer tissues (Fig. 2A). Confocal fluorescence analyses showed that M1-type macrophages were substantially reduced, while M2-type macrop...
Monoclonal antibody Ber EP4 distinguishes basal-cell carcinoma from squamous-cell carcinoma of the skin. Am J Dermatopathol 1993;15:452–455. 3 Jones MS, Helm KF, Maloney ME. The immunohisto- chemical characteristics of the basosquamous cell carcinoma. Dermatol Surg 1997;23:181–184. 4 Beer...
Previous studies of lymphoma series have reported the expression of apoptotic and cell cycle proteins. Our aim was to study these markers in our pediatric patients and correlate them with their outcome. Immunohistochemical staining with monoclonal antibodies anti-p53, bcl-2, p21, and mdm2 were ...
Recombinant Rabbit Monoclonal antibody Product Name Pellino 1 Rabbit mAb Background E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6...
The paraffin sections were stained with either monoclonal anti-NOLC1 (A, C–E) or the control IgG (B, F). The NOLC1 immunoreactivity was seen clearly in the nucleoli of the tumor cell (arrows) in the tumor nests, but not in the stromal cells or in the normal squamous metaplastic ...
Interactions between neutrophils and other (immune) cells are key in exerting their function, and the interaction networks observed in cancer are often highly reminiscent of those seen in other immunological diseases. Neutrophils modulate the efficacy of cancer therapies, and can also serve as biomarker...