to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. CD55 has been studied to have a role in prostate cancer growth and survival. Analyte Specific Reagent How to use the Panel Builder ...
The IFN-omega gene is not expressed in unstimulated cells. Viral infection results in expression of the gene giving rise to the N-glycosylated protein consisting of 172 or 174 amino acids and an apparent molecular mass of about 25kDa. A single carbohydrate group consists mainly of biantennary ...
Bispecific antibody: A recombinant protein that includes antigen-binding fragments of two different monoclonal antibodies, and is thereby capable of binding two different antigens. In some embodiments, bispecific antibodies are used for cancer immunotherapy by simultaneously targeting, for example, both CTL...
the rabbit antiserum did not react with the NSs protein of CCSV because the presence of a major population of IgG targets on epitopes, which are different from those targeted by the MAb. Results from present studies of serological analysis indicate that CaCV is closely, but CCSV is distantly...
The analysis is not driven by the aim to chromatographically resolve sample components, e.g. protein isoforms, but by the intention to rapidly desalt and introduce a sample into the MS system in a quick and easy manner to obtain intact mass information and confirm product identity with high ...
pH 6.5. Purity was assessed by SDS-PAGE and shown to be greater than 95% heavy and light chain. Endotoxin levels were less than 0.125 EU/mL. Specificity of CoVIC-96 was determined by binding to full length SARS-CoV-2 Spike protein expressed in HEK-293T/17 cells and lack of binding ...
is a sugar-phosphate backbone nucleic acid polymer with a strong negative charge which, importantly, has largely consistent physicochemical characteristics regardless of the protein sequence it encodes. As a direct consequence, the production and purification process does not need to be tailored for ...
CD44 is a polymorphic integral membrane protein, which binds to hyaluronic acid (HA), and contributes to cell-matrix adhesion, cell proliferation, migration, and tumor metastasis [7]. When the CD44 is transcribed, its pre-messenger RNA can be received alternative splicing and maturated into mRNAs...
By doing so, a significant cluster of 10 patients (named patient group 1) that had received mitazalimab at either 600 µg/kg or 900 µg/kg was apparent (p < 0.05). The remaining patients (n = 14, named patient group 2) did not cluster in a significant way (Figure 3A). The ...
Dynamic contrast-enhanced-MRI (DCE-MRI) is able to study bone marrow angiogenesis in patients with multiple myeloma (MM) and asymptomatic precursor diseases but its role in the management of MM has not yet been established. The aims of this prospective study was to compare DCE-MRI-based parame...