After DNAse I treatment, CHO and YAC-IRS had an intensity of 85% but IRS-20 had an intensity of 60%, when compared with the controls. DNAse I sensitivity differences between the cell lines indicate that overall conformation of chromatin might contribute to radiation sensitivity of the IRS-20...
SensitivityThe minimum detectable dose of this kit is typically less than 34pg/mL. Specificity This assay has high sensitivity and excellent specificity for detection of Deoxyribonuclease I (DNASE1). No significant cross-reactivity or interference between Deoxyribonuclease I (DNASE1) and analogues was ...
In contrast, the DNase Activity Assay Kit (Fluorescence) can detect DNase contamination within 30 minutes, and the kit is high sensitivity, easy to use. Moreover, the DNase and RNase Activity Assay Kit (Fluorescence) have been designed to work together seamlessly for simultaneous quantitative detec...
The DNA-binding activity measured by the DNase I sensitivity assay represents an important function of the protein in viral replication because three of five mutants tested were thermolabile for this activity. A fourth mutant encoded a ... CK Lee,DM Knipe - 《Journal of Virology》 被引量: 85...
The results demonstrate that DNA methylase activity of rat liver of Diabetic Nephropathy is obviously lower than the control, and its genome DNA possesses higher sensitivity to Dnase I than that of the control. However, DNA methylase activity of rat liver of Diabetic Nephropathy treated with ...
To confirm the existence of a 5′ to 3′ gradient of accessibility, we have recently developed a high-resolution polymerase chain reaction (PCR) assay for DNase I sensitivity. Using this novel DNase I assay, we have reliably detected position- and time-dependent gradients of chromatin ...
Target Deoxyribonuclease I (DNASE1) Reactivity Cow Tested Applications CLIA Recommended dilutions Optimal dilutions/concentrations should be determined by the end user. Test Range 1.56 ng/ml - 100 ng/ml Sensitivity < 0.62 ng/ml Validity The validity for this kit is 6 months. Storage Store at ...
High sensitivity and reproducible results Highly experienced technicians Tailored experimental design for specific requirements Best price in the market Please feel free to contact us for more information of our professional DNase I footprinting assay service. ...
sensitivity for identifying driver genes8,9,10. In this study, we have analyzed whole genome sequences for 657 breast cancer samples and more than one thousand tumors across 19 additional cancer types to detect non-coding driver mutations. We focused on analyzing DNase I hypersensitive sites (...
Using DNase I digestions of intact nuclei in conjunction with NGS, known as DNase- seq, allowed for genome-wide identification of DHSs with unmatched specificity, sensitivity, and throughput [6]. The improved quality of NGS data has made DNase- seq a preferred method of...