Incubates which include candidate agents which alter transcription factor binding deviate from control incubates in terms of label signal - typically, binding is disrupted and the signal is diminished. In a preferred embodiment, the entire process is performed by a computer-controllable electromechanical ...
Cooperation and cooperativity of transcription factors As discussed above, highly expressed TFs can directly bind to DNA, although ultimately this depends on a trade-off among effective concentrations, interaction constants, and number of potential binding sites. To win on all accounts, some TFs contai...
2010 . Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities . Genome Res 20 ( 6 ): 861 – 873 ... A Jolma,T Kivioja,J Toivonen,... - 《Genome Research》 被引量: 606发表: 2010年 FlyFactorSurvey: a database of Drosophila transcription...
Short Communication DNA-binding transcription factor NF1A negatively regulates JC virus multiplicationJC virus (JCV) DNA replication occurs in the nuclei of ... V Ravichandran,EO Major 被引量: 0发表: 0年 MEK1/2 Inhibitors Block Basal and Transforming Growth Factor 1-Stimulated JC Virus Multi...
Octamer DNA binding transcription factor-1 (O... Abdul,Rauf,Shakoori,... - 《Journal of Cellular Biochemistry》 被引量: 6发表: 2012年 Identifying transcription factors with cell-type specific DNA binding signatures Transcription factors (TFs) bind to different parts of the genome in different ...
Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains 2018, Cell Show abstract The Human Transcription Factors 2018, Cell Show abstract JASPAR 2018: Update of the open-access database of transcription factor binding profiles and its web framework 2018, Nu...
Trans -activation and DNA-binding properties of the transcription factor, Sox-18 来自 国家科技图书文献中心 喜欢 0 阅读量: 39 作者:Hosking,Brett,M.,Muscat,George,E.O.,Koopman,Peter,A.,Dowhan 摘要: Sox-18 is a member of the Sox multi-gene family (Sry-related HMG-box gene). We have ...
Binding transcription factor to DNA Double-strand DNA (NF-kB target sequence) was immobilized on a sensor, and the reaction of transcription factor (p50) and the signal amplification (sensitization) by antibody were observed.1.Protocol The measurement was made with the following conditions: NAPiCO...
E. Transcription factors: from enhancer binding to developmental control. Nat. Rev. Genet. 13, 613–626 (2012). CAS PubMed Google Scholar Morgunova, E. & Taipale, J. Structural perspective of cooperative transcription factor binding. Curr. Opin. Struct. Biol. 47, 1–8 (2017). CAS Pub...
The results indicated that PEG3 likely functions as a transcriptional repressor for these two loci. Overall, the current study provides a set of genomic targets and also redefines the DNA-binding motif for the imprinted transcription factor PEG3. 展开 ...