Unbound transcription factor is then removed or washed from the solid substrate and labelled, sequence-specifically bound transcription factor is detected. Incubates which include candidate agents which alter transcription factor binding deviate from control incubates in terms of label signal - typically, ...
转录因子(Transcription factor,也称反式作用因子)是生物学中极为重要的一类蛋白质,它们在基因表达调控中发挥着核心作用。
Transcription factors: specific DNA binding and specific gene regulation Specific recognition of cis-regulatory regions is essential for correct gene regulation in response to developmental and environmental signals. Such DNA se... AL Todeschini,A Georges,RA Veitia - 《Trends in Genetics》 被引量: ...
DNA-dependent formation of transcription factor pairs alters their 552 binding specificity【Nature丨转录因子结合核小体的五种方式(全景图)】 总而言之,DNA打包到核小体上,会使转录因子更难接近DNA。而这项研究向我们展示了转录因子在困难面前,通过其他多种形式接近核小体上的DNA,获取基因组中的重要信息,控制细...
Experimental analysis and computer prediction of CTF/NFI transcription factor DNA binding sites J. Mol. Biol., 297 (2000), pp. 833-848 View PDFView articleView in ScopusGoogle Scholar Roulet et al., 2002 E. Roulet, S. Busso, A.A. Camargo, A.J. Simpson, N. Mermod, P. Bucher High-...
Analysis of the sequence of Rrn3 identified a domain with sequence similarity to the DNA binding domain of heat shock transcription factor 2. Randomization, or deletion, of the amino acids in this region in Rrn3, amino acids 382–400, abrogated its ability to bind DNA, indicating that this ...
本文提介绍了scFAN(single-cell factor analysis network单细胞因子分析网络),这是一种深度学习模型,可以预测单个细胞中全基因组的转录因子结合网络。 scFAN包括对大量的数据进行“预训练模型”训练,然后使用DNA序列数据,汇总的相似scATAC-seq数据和可定位性数据的组合,将其用于预测单细胞水平上的转录因子结合。
【transcription factor】意思是【转录因子】。【转录因子定义】转录因子(transcription factor)是一群能与基因5`端上游特定序列专一性结合，从而保证目的基因以特定的强度在特定的时间与空间表达的蛋白质分子。【转录因子结合特点】转录因子的结合位点（transcription factor binding site，TFBS）是转录因子调节...
Binding transcription factor to DNA Double-strand DNA (NF-kB target sequence) was immobilized on a sensor, and the reaction of transcription factor (p50) and the signal amplification (sensitization) by antibody were observed. 1.Protocol The measurement was made with the following conditions: ...
A set of coding sequences of both DNA-binding domains (DBDs) and full-length P. syringae TFs were compiled based on annotations in the DBD: Transcription-factor prediction database (www.transcriptionfactor.org)22, altogether resulting in 301 TFs included in the present study (Fig. 1a). ...