A role for DNA primase in coupling DNA replication to DNA damage response. EMBO J. 16 : 639-650.Marini F, Pellicioli A, Paciotti V, Lucchini G, Plevani P, Stern D F, Foiani M. A role for DNA primase in coupling DNA replication to DNA damage response. EMBO J. 1997; 16 :639–...
Communication between DNA polymerases and Replication Protein A within the archaeal replisome The single stranded DNA binding protein RPA plays a pivotal role in DNA replication. The archaeal RPA hosts a WH domain that interacts with the DNA primase and the replicative polymerase PolD. Here the au...
In eukaryotes, DNA polymerases (Pols)3 α, δ, and ϵ jointly support DNA replication, and their overall roles in this process have been defined (1). The initiation of DNA replication is catalyzed by the Pol α-primase complex, composed of the Pol α complex (p180-p70) associated with ...
Bacterial DNA replication fork. (a) Simplified overview. The leading strand is initiated with an RNA primer and then elongated with a DNA polymerase, pol III. The lagging strand is synthesized in a series of fragments, each initiated by primase, which inserts short sequences of RNA primers ...
During DNA replication, which strand is the lagging strand? Why can't both strands be synthesized in the same manner? What is topoisomerase? Describe its role in DNA replication. How can DNA be transcribed to RNA? What is the type of replication that DNA undergoes in order to be copied?
Explain in detail. Binary fission allows cells to grow, replication of DNA, and separates cytoplasm and DNA. Describe the process of DNA replication, including the role of the origins of replication and replication forks. Describe the proofreading mechanism during DNA replication. ...
DNA replication in almost all organisms depends on the activity of DNA primase, a DNA-dependent RNA polymerase that synthesizes short RNA primers of defined size for DNA polymerases. Eukaryotic and archaeal primases are heterodimers consisting of small catalytic and large accessory subunits, both of...
DNA replication(07-6)改 DNAReplication PARTIANOVERVIEW DNAReplication 1)Semi-conservativemechanism（半保留机制）2）Replicons(复制子),origins（复制起点）,andtermini（复制终点）3）Semi-discontinuousreplication（半不连续复制）4）RNApriming（引导）Thecharacteristicofreplication:Semi-conservativeSemi-discontinuous S...
3-ohlagging strand of lagging strand of 环状环状 dna replication dna replication lagging strand of lagging strand of 线状线状 dna replication dna replication but 3-oh ? a)a) watson j. d watson j. d t t7 7 phage phage direct repeat in the end of linear dna concatermer between two ...
Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication In wild-type diploid cells of Saccharomyces cerevisiae, an HO endonuclease-induced double-strand break (DSB) at the MAT locus can be efficiently repaired b... A Malkova,EL Ivanov,...