3. J. S. Fridman, S. W. Lowe, Control of apoptosis by p53. Oncogene 22, 9030–9040 (2003).4. W. P. Roos, B. Kaina, DNA damage-induced cell death by apoptosis. Trends Mol. Med. 12, 440–450 (2006).5. A. V. Gudkov, E. A. Komarova, The role of p53 in determining sen...
DNA damage-induced cell death: lessons from the central nervous system. Borges HL,Linden R,Wang JY. Cell Research . 2008Borges HL, Linden R, Wang JY. DNA damage-induced cell death: lessons from the central nervous system. Cell Res 2008;18:17-26.H.L. Borges, R. Linden, J.Y. Wang,...
DNA damage-induced cell death relies on SLFN11-dependent cleavage of distinct type II tRNAsTranscriptome analysis reveals a strong positive correlation between human Schlafen family member 11 (SLFN11) expression and the sensitivity of tumor cells to DNA-damaging agents (DDAs). Here, we show that ...
近日,美国南佛罗里达大学、英国莱斯特大学的研究人员在《自由基生物学和医学》杂志上发表了一篇题为" Redox modulation of oxidatively-induced DNA damage by ascorbate enhances both in vitro and ex-vivo DNA damage formation and cell ...
DNA damage-triggered signaling and execution of apoptosis is cell-type- and genotoxin-specific depending on the p53 (p63 and p73) status, death-receptor responsiveness, MAP-kinase activation and, most importantly, DNA repair capacity. Because most clinical anti-cancer drugs target DNA, increasing ...
Various modes of cell death induced by DNA damage. The consequences of DNA damage depend on the cell type and the severity of the damage. Mild DNA damage can be repaired with or without cell-cycle arrest. M... Surova,O,Zhivotovsky,... - 《Oncogene》 被引量: 146发表: 2013年 Suppressi...
近日,美国南佛罗里达大学、英国莱斯特大学的研究人员在《自由基生物学和医学》杂志上发表了一篇题为" Redox modulation of oxidatively-induced DNA damage by ascorbate enhances both in vitro and ex-vivo DNA damage formation and cell death in melanoma cells "的研究论文。
Our data therefore suggest roles for TERT in modulating such cell deaths.doi:10.1016/S0165-3806(01)00237-1Chengbiao LuWeiming FuMark P MattsonElsevier B.V.Developmental Brain ResearchLuC,etal.Telomerase protects developing neurons against DNA damage-induced cell death.Brain Research Developmental Brain...
相关研究结果近期发表在Free Radical Biology and Medicine期刊上,论文标题为“Redox modulation of oxidatively-induced DNA damage by ascorbate enhances both in vitro and ex-vivo DNA damage formation and cell death in melanoma cells”。 这些作者发现与正常皮肤细胞相比,黑色素瘤细胞的DNA损伤更多,抗氧化防御...
相关研究结果近期发表在Free Radical Biology and Medicine期刊上,论文标题为“Redox modulation of oxidatively-induced DNA damage by ascorbate enhances both in vitro and ex-vivo DNA damage formation and cell death in melanoma cells”。 这些作者发现与正常皮肤细胞相比,黑色素瘤细胞的DNA损伤更多,抗氧化防御...