DBD, DNA-binding domain; HMG, high mobility group; IHF, integration host factor; NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells; OCT-1, octamer binding transcription factor 1; TBP, TATA-box binding protein; TFIIIA, transcription factor IIIA. The HMG proteins are a di...
Chen, H.H. Yang, A graphene oxide (GO)- based molecular beacon for DNA-binding transcription factor detection, Nanoscale 4 (2012) 3655e3659.Jing-Jing Liu,Xiao-Rong Song,Yi-Wei Wang.A graphene oxide (GO)-based molecular beacon for DNA-binding transcription factor detection. NANOSCALE . 2012...
Transcription factors respond to multilevel stimuli and co-occupy promoter regions of target genes to activate RNA polymerase (RNAP) in a cooperative manner. To decipher the molecular mechanism, here we report two cryo-electron microscopy structures of A
Nucleosome depletion around transcription factor-binding sites is partly encoded in the nucleosome affinity landscape of the genome and might assist in directing factors to their appropriate genomic sites. Differences in the intrinsic nucleosome affinity landscapes in which factor-binding sites are embedded...
double-stranded DNA binding protein kinase activity protein serine/threonine kinase activity DNA-dependent protein kinase activity protein binding ATP binding transcription factor binding enzyme binding poly(A) RNA binding non-receptor serine/threonine protein kinase protein modifying enzyme 参与通路 somito...
在猕猴桃和香蕉的其他NAC转录因子中也观察到了相同的结合基序。这些结果表明果实中NAC的结合基序是保守的。GO富集分析结果显示,启动子与PpNAC1结合的基因参与了果实的有机酸、蔗糖代谢等初级代谢过程,苯丙烷代谢、内酯代谢等次级代谢过程,激素代谢及反应,还与果实发育及防御反应过程有关。
2023年11月22日,浙江大学张波教授课题组研究成果,发表在Plant Physiology期刊上(影响因子7.4),文章题目为Transcription factor PpNAC1 and DNA demethylase PpDML1 synergistically regulate peach fruit ripening。该研究使用了DNA亲和纯化测序(DAP-seq)技术鉴定了PpNAC1转录因子的结合基序和靶基因。研究发现转录因子PpNAC...
UvrC is a single-stranded DNA-binding protein and binds to it with a relatively high affinity. UvrC is a catalytic subunit of the UvrABC endonuclease. Mutations in the C-terminal region of UvrC are extremely sensitive to UV and defective in 5′-incision activity. The 314 C-terminal am...
These represent CpG-poor distal regulatory regions as evidenced by location, DNase I hypersensitivity, presence of enhancer chromatin marks and enhancer activity in reporter assays. LMRs are occupied by DNA-binding factors and their binding is necessary and sufficient to create LMRs. A comparison of...
(16/28) for transcription factor binding, including Ikaros (IKZF1, IKZF2), MYC, and MAX, which can form multi-protein repressive complexes (Supplementary Table7, Supplementary Data File2). In contrast to the larger set of neutrophil genes identified in GO analysis, the 16 genes represented ...