et al. The role of the DNA-binding One Zinc Finger (DOF) transcription factor family in plants. Plant Science, v. 209, n. 1, p. 1-14, 2013.Noguero M, Atif RM, Ochatt S, Thompson RD (2013) The role of the DNA-binding one zinc finger (DOF) transcription factor family in plants...
A vast number of different transcription factors and other regulatory proteins bind DNA by means of a relatively small number of DNA-binding domains. The best known of these motifs are the helix-turn-helix, helix-loop-helix, leucine zipper, and zinc finger. Both the helix-turn-helix (HTH) ...
Dof(DNAbindingwithonefinger)是植物所特有的一类转录因子,它含有一个独特的富含Cys残基的单锌指保守结构域,命名为Dof结构域。目前,在多种单子叶植物和双子叶植物中都发现了Dof蛋白,它们在高等植物基因表达调控中起作用。水稻的Dof转录因子家族包括30个Dof基因,记为OsDof-1至OsDof-30,分为a、b、c、d4个亚家族...
SMC1和SMC3的肽链的两端在头部形成了一种特殊的空间结构,叫做核苷酸结合结构域(nucleotide-binding domain, NBD),而且它还具有水解ATP的活性。正是依靠这种结构,SMC1-SMC3在头部(heads)通过ATP的相互结合,构成了粘合素的“内门”(inner gate)。在下图中,A、B、S是蛋白质的三种不同的空间结构。(它们其实是有全称...
The zinc finger, one of the major structural motifs used for sequence specific DNA binding, has been identified in many regulatory proteins. By analogy, involvement in nucleic acid recognition has been implied for proteins that contain two cysteines and two histidines, spaced in accordance with the...
DNA binding with one finger (Dof) transcription factors play important roles in plant growth and abiotic stress responses. Although genome-wide identification and analysis of the DOF transcription factor family has been reported in other species, no relevant studies have emerged in wheat. The aim of...
激活的 ATM 磷酸化羧末端结合蛋白反应蛋白 (C-terminal-binding Protein Interacting Protein,CtIP),再与乳腺癌 1 型易感蛋白 (Breast Cancer Type1 Susceptibility Protein,BRCA1) 相互作用,形成 BRCA1/MRN/CtIP 复合体,促进 DNA 末...
2a) to probe the DNA binding of the BED domain. As a control, a randomized 17-mer (ran17) was used that had no common features with LE11-27. The DNAs were titrated with an increasing amount of protein from one to three equivalents and analyzed by size exclusion chromatography (SEC)....
binding logos for all 12 NRs generated for the single DR1 seed sequence shown.eAmino acid sequence of zinc finger 1 for the wild-type RXRα, RXRα DNA-binding domain mutant, wild-type PPARγ, and the PPARγ DNA-binding domain mutant. Altered amino acids are highlighted in gray.fDNA-...
Dof(DNAbindingwithonefinger)是植物所特有的一类转录因子,它含有一个独特的富含Cys残基的单锌指保守结构域,命名为Dof结构域。目前,在多种单子叶植物和双子叶植物中都发现了Dof蛋白,它们在高等植物基因表达调控中起作用。水稻的Dof转录因子家族包括30个Dof基因,记为OsDof-1至OsDof-30,分为a、b、c、d4个亚家族...