Dof(DNAbindingwithonefinger)是植物所特有的一类转录因子,它含有一个独特的富含Cys残基的单锌指保守结构域,命名为Dof结构域。目前,在多种单子叶植物和双子叶植物中都发现了Dof蛋白,它们在高等植物基因表达调控中起作用。水稻的Dof转录因子家族包括30个Dof基因,记为OsDof-1至OsDof-30,分为a、b、c、d4个亚家族...
The Dof (DNA binding with one finger) is a typical example of plant specific transcription factor involved with regulation of diverse genes associated with multifarious roles. Attempts are being made to characterize the Dof gene family of the important vegetable crops namely tomato (Lycopersicum ...
Transcription factors (TFs) involve in activating or inhibiting the activity of RNA polymerase to regulate the spatiotemporal expression of the target genes by recognizing specific DNA sequence elements present in the promoter region of the gene [1]. DNA binding with one finger (Dof) transcription ...
Dof (for DNA binding with one finger) is a family of DNA binding proteins that have been found in diverse plant species. Members of the Dof family comprise a Dof domain or an active variant or fragment thereof, which is a highly conserved amino acid sequence involved in DNA binding. The ...
In plants, DOF (DNA-binding with one finger) TFs, which contain a conserved CX2CX21CX2C motif, regulate a wide range of developmental and environmental responses by binding to specific target genes in vivo6, but their DNA-binding site has only been described by a simple consensus motif, ...
In a phenotypic screen of plants constitutively overexpressing DOF (DNA-binding-with-one-finger) transcription factors under the control of the Cauliflower... S Aleksandra,J Szymon,S Maciej,... 被引量: 0发表: 2021年 Genetic interactions between brassinosteroid-inactivating P450s and photomorphogenic ...
Fig. 2. Amino acids of the DNA binding domain. This sequence shows the complexed zinc ions (Zn2 +) and the zinc finger structures with the “knuckles” being composed of the two or five amino acids between the cysteines complexed with zinc. 1 Antigenic Sites Several antibodies have been ...
The DNA-binding domain of the RARs is 66 amino acids in length, and its structure has been determined by X-ray crystallographic studies. The two zinc fingers fold into a globular domain such that residues of the first zinc-binding finger (C1) make specific contacts with DNA through ...
DNA is capable of self-assembling into a wide range of user-defined structures and so can be used as a scaffold to arrange binding motifs with nanometre precision. Now, DNA has been used to accurately display aptamers that fit the repeated epitope pattern of a dengue viral antigen to produce...
Some ribozymes are nucleases and can include base-pairing regions that enable specific binding and cleavage of a target RNA molecule. Rights and permissions Reprints and permissions About this article Cite this article Lange, S., Takata, Ki. & Wood, R. DNA polymerases and cancer. Nat Rev ...