This Review discusses the major advances and changes made over the past 3 years to our understanding of chimeric antigen receptor (CAR) T cell efficacy and safety. Recently, the field has gained insight into how various molecular modules of the CAR in
a broad heterogeneous group of tumours that includes clear-cell sarcoma of the kidney, congenital mesoblastic nephroma, malignant rhabdoid tumour of the kidney, renal-cell carcinoma, renal medullary carcinoma and other rare histologies. The differential diagnosis of ...
how MSCs aid in (i) enabling replicative immortality to cancer cells (ii) sustaining proliferative signal of cancer cells and cancer stem cells (iii) its action on epithelial and mesenchymal transition and metabolism of cancer cells (iv) how MSCs can evade growth suppressor (v) resist cell ...
This section on biology news includes new research related to many related subjects such as biochemistry, genetics, cytology, and microbiology. Popular sub-topics includeBiotechnology,DNA,Microbiology,Neurology,Evolutionary Biology,Genetics,Stem Cells,Neuroscience,Bioengineering, andCell Biology. ...
The assigned structure high- lighted the presence of nine stereocenters; six of which lie in the macrocycle and three in the terminal δ-lactone.42 Biological evaluation showed that leiodermatolide exhibited potent anticancer activity, in particular against a range of drug-resistant cancer cell lines...
For any tumor type, there are genes that are really important in cancer cell initiation and progression. For some of the genes, we are already able to do a molecular diagnosis. Only when you are able to make a molecular diagnosis and you have an effective targeted therapy for that specific...
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell 2011; 146: 247–261. Article CAS Google Scholar Harris MA, Clark J, Ireland A, Lomax J, Ashburner M, Foulger R et al. The Gene Ontology (GO) database and informatics resource. Nucleic Acids Res ...
In spite of the wonderful achievements of modern science, it seems impossible to get the public to think in scientific terms. This is doubtless due to a
but treatment of some affected individuals remains challenging. Challenges are also posed by the intratumoural heterogeneity of biomarkers. Furthermore, preclinical models of Wilms tumour, from cell lines to organoid cultures, have evolved. Despite these many achievements, much still remains to be disc...
Which of the following scientists developed the most widely-used staining technique that differentiates bacteria based on differences in cell wall structure? A) Lister B) Gram C) Pasteur D) Koch Explain the significance of any two historical achievements in ...