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This Review discusses the major advances and changes made over the past 3 years to our understanding of chimeric antigen receptor (CAR) T cell efficacy and safety. Recently, the field has gained insight into how various molecular modules of the CAR in
Due to the discoveries in the past decades, including "neocentromeres" and "centromere inactivation", it is now believed that the centromere identity is determined by epigenetic mechanisms. This review will present recent progress in plant centromere biology.doi:10.1007/s11427-015-4818-3FENG Chao...
Recent advances and discoveries in the mechanisms and functions of CAR T cells Abstract This Review discusses the major advances and changes made over the past 3 years to our understanding of chimeric antigen receptor (CAR) T cell efficacy and safety. Recently, the field has gained insight int...
Recent discoveries in cell signalling have provided greater understanding of the biology that underlies melanoma, and these advances are being exploited to ... Gray-Schopfer,V,Wellbrock,C,Marais,R - 《Nature》 被引量: 2002发表: 2007年 Review Article Melanoma biology and new targeted therapy Recent...
PURPOSE OF REVIEW: Research into the basic biology of telomeres continues to reveal details relevant to fundamental aspects of human cancer. The goal of this review is to highlight discoveries made within the last year, with emphasis on their relevance to cancer prevention, diagnosis, prognostics,...
Nutrition science aims to create new knowledge, but scientists rarely sit back to reflect on what nutrition research has achieved in recent decades. Methods: We report the outcome of a 1-day symposium at which the audience was asked to vote on the greatest discoveries in nutrition since 1976 ...
In short, we anticipate that the use of lipidomics will lead to exciting new discoveries in the field of lipid biology in the coming years. References and recommended reading Papers of particular interest, published within the period of review, have been highlighted as: Acknowledgements The Kamp...
NADs development is inseparable from the major discoveries in fundamental molecular biology and the continuous observations of life activities (Fig.1). In 1869, Friedrich Miescher discovered a new molecule called “nuclein” from white blood cells, which marked the beginning of DNA discovery.28However...
A selection from the many excellent presentations and posters are described with an emphasis on new compounds, new methods to identify cancers, and recent discoveries that may change how we treat cancer. (c) 2004 Prous Science. All rights reserved.关键词:...