The feasibility of embryonic stem cells to combine with silk fibroin for neural differentiation was invaluable and unknown. We suspended the ES cells into EBs and then transferred them to three different substrates-coated 35 mm dishes including gelatin, Bombyx mori silk fibroin (SF) and Tussah ...
The potential of human embryonic stem (hES) cells to differentiate into cell types of a variety of organs has generated much excitement over the possible use of hES cells in therapeutic applications. Of great interest are organs derived from definitive endoderm, such as the pancreas. We have foc...
Polycomb repressive complex 1 (PRC1) is an important regulator of gene expression and development. PRC1 contains the E3 ligases RING1A/B, which monoubiquitinate lysine 119 at histone H2A (H2AK119ub1), and has been sub-classified into six major complexes
Embryonic stem cells can proliferate indefinitely and are capable of differentiating into derivatives of all three embryonic germ layers in vitro, including the neural lineage. The main objective of this study is to test the effects of neural stem cell conditioned medium on the neural differentiation...
Although the majority of recent studies in human embryonic stem cell (hESC) differentiation have focused on the role of growth factors, such as FGF, TGFand WNT, relatively little is known about the role of ECMP-integrin signaling in this process. Moreover, current strategies to direct hESC ...
Human embryonic stem cell-derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential Blood, 105 (2005), pp. 617-626 View PDFView articleView in ScopusGoogle Scholar Wang et al., 2004 L. Wang, F. Shojaei, K. Levac, C....
Bone tissue formation from human embryonic stem cells in vivo. Although the use of embryonic stem cells in the assisted repair of musculoskeletal tissues holds promise, a direct comparison of this cell source with adul... JL Tremoleda,NR Forsyth,N Khan,... - 《Cloning & Stem Cells》 被引...
Pluripotent embryonic stem cells can give rise to neuroectodermal derivatives in culture. This potential could be harnessed to generate neurons and glia for cell-replacement therapies in the central nervous system and for use in drug discovery. However, current methods of neural differentiation are empi...
Embryonic stem (ES) cells are characterized by pluripotency, defined as the developmental potential to generatecell lineagesderived from all three primarygerm layers. In the past decade, great progress has been made on the cell culture conditions, transcription factor programs and intracellularsignaling ...
Here we found that FZHY enhanced hepatocyte differentiation from human embryonic stem cells (hESC). After treatment with FZHY, albumin expression was consistently increased during differentiation and maturation process, and expression of metabolizing enzymes and transporter were also increased. Importantly,...