Occludin-deficient embryonic stem (ES) cells were generated by targeted disruption of both alleles of the occludin gene. When these cells were subjected to suspension culture, they aggregated to form simple, and then cystic embryoid bodies (EBs) with the same time course as EB formation from ...
15 Embryonic stem cells can be used in cell replacement therapies. Embryonic stem cells can differentiate into any type of body cell but cannot form a whole organism.Which of the options, A to D, is the type of stem cell being described? A pluripotent B totipotent C unipotent D multipotent...
Differentiation and characterization of metabolically functioning hepatocytes from human embryonic stem cells Stem cells, 28 (2010), pp. 674-686, 10.1002/stem.315 View in ScopusGoogle Scholar 9 H. Basma, A. Soto-Gutierrez, G.R. Yannam, L. Liu, R. Ito, T. Yamamoto, et al. Differentiation...
A cell that can differentiate into all cell types of the adult organism is known as ( ). Such cells are called meristematic cells in higher plants and embryonic stem cells in animals.相关知识点: 试题来源: 解析 pluripotent 反馈 收藏
The first embryonic cells that arise from the division of the zygote arethe ultimate stem cells; these stems cells are described as totipotent because they have the potential to differentiate into any of the cells needed to enable an organism to grow and develop. ...
Human embryonic stem cells (hESCs) readily differentiate to somatic or germ lineages but have impaired ability to form extra-embryonic lineages such as placenta or yolk sac. Here, we demonstrate that naive hESCs can be converted into cells that exhibit the cellular and molecular phenotypes of human...
Embryonic stem (ES) cells have the potential to proliferate in vitro in an undifferentiated and pluripotent state. Theoretically, ES cells are capable of unlimited proliferation in vitro. ES cells spontaneously differentiate into derivatives of all three primary germ layers: endoderm, ectoderm and ...
Stem cells Cells that have the dual capacity to self-replicate and to differentiate into specialized derivatives Nuclear transplantation to Derivation of stem cells from the product of the nuclear transfer procedure (usually the produce stem cells blastocyst). Also referred to as therapeutic cloning...
Remarkably, ChIP-chip studies of Brachyury occupancy in differentiating mouse embryonic stem cells show that mouse Brachyury often binds (AC)≥ 6 microsatellite repeats (Evans et al., 2012), thus suggesting a possible evolutionary conservation of this mechanism of regulation of gene expression. View ...
We developed a protocol that mimics mammalian liver development, to differentiate cells with pluripotent characteristics to hepatocyte-like cells. The protocol supports the stepwise differentiation of human embryonic stem cells (ESC) to cells with characteristics of primitive streak (PS)/mesendoderm (ME)...