Embryonic stem (ES) cells are pluripotent cells whose developmental state is equivalent to cells of the inner cell mass in the blastocyst-stage embryo. This unit presents a method of producing differentiated ES cells in which the cells are first aggregated on a less adhesive surface to form ...
Inhibition of β-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells J. Cell Biol., 211 (2015), pp. 39-51 CrossrefView in ScopusGoogle Scholar Clevers, 2006 H. Clevers Wnt/β-catenin signaling in development and disease Cell, 127 (2006), pp. 469-480 View in ...
Differentiation of Human Parthenogenetic Embryonic Stem Cells into Functional Hepatocyte-like CellsStem cell and tissue engineering-based therapies for acute liver failure (ALF) have been limited by the lack of an optimal cell source. We aimed to determine the suitability of human parthenogenetic ...
The potential of human embryonic stem (hES) cells to differentiate into cell types of a variety of organs has generated much excitement over the possible use of hES cells in therapeutic applications. Of great interest are organs derived from definitive e
www.nature.com/scientificreports OPEN received: 27 August 2015 accepted: 27 November 2015 Published: 06 January 2016 Enhancement of hepatocyte differentiation from human embryonic stem cells by Chinese medicine Fuzhenghuayu Jiamei Chen1,2,3,4, Wei Gao2,3,5, Ping Zhou2,3, Xiaocui Ma2...
The recent isolation of human embryonic stem cells has raised a lot of interest for the potential of transposing our knowledge of lineage-specific differentiation of embryonic stem cells to cell-based therapy of human disease. Recent reports have provided insights into the specific differentiation of ...
Embryonic stem (ES) cells were used as a model system to understand the signalling events in pancreas development. ES cells were differentiated through known precursor stages towards the tissue of interest in order to recapitulate development in vitro. Thus, protocols directing differentiation of mouse...
The germ cells come from the primordial germ cells(PGCs),in vivo differentiation mechanism of which has been basically understood.With the development of germ cell studies,in vitro induction of germ cells has become the reality.Embryonic stem cells(ESCs) can be induced to differentiate into epiblas...
Human embryonic stem (hES) cells, derived from blastocysts, are capable of unlimited self-renewal and differentiation into all cell lineages of the body. B... H Fong,KA Hohenstein,PJ Donovan - 《Stem Cells》 被引量: 466发表: 2008年 Regulation of Spermatogonial Stem Cell Self-Renewal in Mamm...
Directed differentiation of human pluripotent stem cells - human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) - toward ... I Faravelli,M Bucchia,P Rinchetti… - 《Stem Cell Research & Therapy》 被引量: 41发表: 2014年 Part C: Directed Differentiation of Huma...