PURPOSE: Provided are a diagnosis method of BRCA1 mutation and a diagnosis immuno chip using the same, thereby examining the possibility of disease incidence, such as breast cancer and ovarian cancer. CONSTITUTION: Human BRCA1 mutation can be diagnosed in breast milk of an animal, wherein the ...
BRCA1基因突变的1例晚期卵巢癌患者合并FN的诊治体会 获取原文 开具论文收录证明 >> 期刊封面封底目录下载 >> 页面导航 摘要 著录项 相似文献 相关主题 摘要 cqvip:对于晚期上皮性卵巢癌(EOC)患者而言,标准的治疗模式是以手术治疗为主,术后辅以铂类为主的化疗[1]。近20年来,随着新的靶向治疗药...
8. The method of claim 1, further comprising classifying the cell sample ER(+) (estrogen receptor positive) or ER(−) (estrogen receptor negative) based on a second expression profile comprising the expression levels of a second plurality of genes in said cell sample, said second plurality ...
With ITS1 PCR, irrespective of the addition of Q-solution, we observed a higher number of positives for all the trypanosome species compared to ITS1 TD PCR and nested ITS PCR. Adding Q-solution in the PCR mixture of ITS1 TD PCR profoundly decreases the number of positive reactions from ...
Cetuximab therapy is the major treatment for colorectal cancer (CRC), but drug resistance limits its effectiveness. Here, we perform longitudinal and deep proteomic profiling of 641 plasma samples originated from 147 CRC patients (CRCs) undergoing cetuximab therapy with multi-course treatment, and 90...
a positive correlation (PCC = 0.8198) occurred between the deconvolution metric RMSE and the detection metric 1 - AUC, as shown in Fig.3b, suggesting that the AUC can also be used to quantify the accuracy of predicted tumor fractions, especially for diagnosis using patient cfDNA since thei...
2. The method for claim 1 further comprising (d) comparing the amount of the one or more biomarkers in the exosomes determined in (c) to one or more positive or negative control amounts, wherein a amount of pBP1 in the exosomes of the subject that is (i) significantly higher than the...
As anticipated, the test set AUC exhibits a positive correlation with the quantity of real data used to train the classifier. Additionally, for data regimes with up to 500 real training samples, there is a distinct performance improvement as the amount of added synthetic data increases. Notably,...
由于BRCA1/2基因没有热点变异, 且变异遍布于2个基因的全长 , 国内对于BRCA1/2基因检测一般采用下一代测序 ( NGS) 或称高通量测序的方法进行检测。 BRCA1/2基因突变分为胚系突变和体细胞突变两种。 胚系BRCA1/2基因突变起源于生殖细胞, 存在于机体的每一个细胞中; ...
Hormone-receptor positive (HR+) breast cancer (BC) (including the luminal A and the luminal B subtypes) is the most common type of tumor in women diagnosed