BMC Cancer (2023) 23:78 https://doi.org/10.1186/s12885-023-10554-6 BMC Cancer RESEARCH Open Access Risk of seizures in a population of women with BRCA‑positive metastatic breast cancer from an electronic health record database in the United States Alexander Liede1,2...
Individuals harboring expected pathogenic variants inBRCA1/2in BioMe, termed “variant positive,” were evaluated for any evidence of personal or family histories of HBOC-related cancers, through extraction of International Classification of Diseases (ICD)-9 and ICD-10 codes from participant EHRs (A...
carried out association analyses by subtype for the following breast cancer characteristics: ER-positive and ER-negative, PR-positive and PR-negative, HER2-positive and HER2-negative, TN breast cancer (that is, negative for ER, PR and HER2) and non-TN (that is, tumor positive for at least ...
Controversy remains as some studies demonstrated no correlation, and others, a positive correlation between BRCA2 mutations in the BRC domain and ovarian cancer patient survival [73,74]. Discrepancies arise in part due to the selection of the BRCA2 mutations (missense, indels, etc.), the number...
Implementing genomics-based screening programs wisely depends on ensuring that testing would be widely available and acceptable to the population, that disease penetrance be high in those screened positive, and that interventions would be cost-effective [26]. These principles are fulfilled by screening ...
Therefore, the aim of the present study was to assess the secretory function of salivary glands, selected salivary biomarkers of redox balance, and oxidative damage to proteins and lipids in subjects with breast cancer as compared to patients without breast cancer, positive or not positive for ...