Immunotherapy using dendritic cell (DC)-based vaccination is an approved approach for harnessing the potential of a patient's own immune system to eliminate tumor cells in metastatic hormone-refractory cancer. Overall, although many DC vaccines have been tested in the clinic and proven to be immuno...
This review discusses the use of dendritic cells in immunotherapy and some of the clinical trials that have been conducted.doi:10.1016/S0093-7754(03)00229-XEdgar G EnglemanElsevier Inc.Seminars in OncologyEngleman, E. G. (2003) Dendritic cell-based cancer immunotherapy. Semin Oncol 30 :23–...
G. Dendritic cell-based immunotherapy: state of the art and beyond. Clin. Cancer Res. 22, 1897–1906 (2016). Article CAS PubMed Google Scholar Garg, A. D., Coulie, P. G., Van den Eynde, B. J. & Agostinis, P. Integrating next-generation dendritic cell vaccines into the current...
DCs can also activate naive and memory B cells31, primarily through their ability to stimulate CD4+T cells (such as T follicular helper cells), which induce B-cell growth and antibody production. Antibody class switching is influenced through the production of factors that activate and induce B-...
Individually prepared immunotherapy (ITx) based on autologous dendritic cells (DCs) represents a new possibility in modern advanced anti-cancer treatment. As an extended evaluation of DC-based medicinal product in an academic phase I/II clinical trial for children, adolescents and young adults with ...
(DCs) from potent stimulators to negative modulators of immunity. Dendritic cell-based immunotherapy attempts to resolve this problem by manipulating the functional characteristics of DCs. Plant-derived polysaccharides (PDPs) can stimulate the maturation of DCs conferring on them the capacity to present...
Whether you’re developing a CAR-T therapy, another type of T-cell immunotherapy, or working with other immune cell types, Gibco CTS products are the superior choice from research to clinic, and beyond. Cell Therapy Systems (CTS) tools, re...
Whether you’re developing a CAR-T therapy, another type of T-cell immunotherapy, or working with other immune cell types, Gibco CTS products are the superior choice from research to clinic, and beyond. Cell Therapy Systems (CTS) tools, reagents, and services, suppo...
Dendriticcell(DC)-basedvaccinationagainstcancerisaspecific immunotherapy withanewtherapeuticapproachforpatientswithcancer. 树突状细胞(DC)为基础的癌症疫苗是一种特异性免疫治疗的新治疗方法的癌症患者。 www.syyxw.com 4. Theimprovedefficacyoverrituximab monotherapymaybe duetoincreasesseeninmonocyte,granulocyte,anddendr...
Dendritic-cell based immunotherapy Based on the above discussion, it is reasonable to postulate that the administration of activated dendritic cells, loaded with tumor-antigens, might be an excellent methodology by which to initiate an anti-tumor immune response. Dendritic cells can be derived by cu...