As DC vaccines virtually have no side effects, they can be used much earlier in adjuvant settings. The full potential of DC-based cancer vaccines has not yet been fully exploited. Its place in cancer immunotherapy will be determined in the upcoming years....
2002. Dendritic cell-based vaccines and therapies for cancer. Expert Opin. Biol. Ther. 2: 919-928.Tatsumi T, Storkus WJ. Dendritic cell-based vaccines and therapies for cancer. Expert Opin Biol Ther 2002;2(8):919–28.Tatsumi T, Storkus WJ. Dendritic cell-based vaccines and therapies ...
Dendritic cell-based vaccines for pancreatic cancer and melanoma Immunotherapies can treat many cancers, including difficult-to-treat cases such as lung cancer. Due to its tolerability, long-lasting therapeutic responses... JJ Mulé - Ann N Y Acad Sci 被引量: 0发表: 2009年 Translational Mini-Re...
Cancer immunotherapy with dendritic cell (DC)-based vaccines has been used to treat various malignancies for more than two decades, however generally showe... N Dobrovolskien?,V Pa?Ukonien?,A Darinskas,... - 《Vaccine》 被引量: 2发表: 2018年 DENDRITIC CELL BASED VACCINES The present inve...
Nanovaccines are nanoscale complexes that accommodate both antigens and immune stimuli that can activate T-cells or DCs upon their in vivo administration (Figure 1) [6]. This review focuses on the use of nanovaccines to generate T-cell mediated active anti-tumor immune responses. First, ...
At the interface between the innate and adaptive immune system, dendritic cells (DCs) play key roles in tumour immunity and hold a hitherto unrealized potential for cancer immunotherapy. Here we review the role of distinct DC subsets in the tumour microe
Keywords : Dendritic cell, Vaccines, Breast cancer, Immune regulation, Immunotherapy Plan Introduction DCs and DC-based vaccines Biology of DCs Preparation and types of DC-based vaccines DC-based vaccines in immunomodulation of BC DC polypeptide vaccine DC gene vaccines Clinical application of DC-based...
Recent advances in our understanding of the immune system and its relationship to cancer have enhanced the therapeutic potential of cancer immunotherapy. The ability to use clinical cell processing to safely and effectively generate novel autologous cell-based therapies has led to a rapid expansion in...
Dendritic-cell-based therapeutic vaccination against cancer Early clinical trials, in which over 1000 cancer patients received dendritic cell (DC) vaccines, tested different vaccine preparations, but they did not al... FO Nestle,A Farkas,C Conrad - 《Current Opinion in Immunology》 被引量: 527...
cell immunity, dendritic cells are increasingly used as adjuvants for vaccination, and the immunogenicity of antigens delivered by dendritic cells has now been shown in patients with cancer. A better understanding of how dendritic cells regulate immune responses will allow us to better exploit these...