Fortunately, however, the disorders of myelin lend themselves well to attempts at structural repair, because central oligodendrocytes are the primary, and often sole, victims of the underlying disease process. Given the relative availability and homogeneity of human oligodendrocyte progenitor cells, the ...
14、te or subacute demyelinating disease involved optic N and spinal cord at the same time.2.Etiology And Pathogenesis :与遗传素质和种族差异有关。西方-脑干;东方-视神经和脊髓;25%MS突发球后视神经炎;多方研究证实白种人对MS易感;非白种人对NMO易感。3.Pathology:Demyelination,plaque of sclerosis, in...
必应词典为您提供Demyelinating-disease的释义,un. 脱髓鞘病; 网络释义: 脱髓鞘疾病;神经脱髓疾病学;去髓鞘性疾病;
Some demyelinating diseases affect the brain and/or spinal cord. Others affect the peripheral nerves that branch out from the brain and spinal cord. The most common demyelinating disease ismultiple sclerosis(MS), an autoimmune disorder in which the immune system attacks myelin of the brain, spinal...
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The prototypical inflammatory demyelinating disease of the CNS is MS, which is traditionally considered to be due to aberrant myelin-reactive T cells that, once activated in the periphery, gain entry to the CNS across a damaged blood–brain barrier. Recent studies, however, indicate that rather ...
Multiple sclerosis (MS) remains the most common primary CNS demyelinating disorder, affecting white and grey matter of the brain, spinal cord and optic nerve.1 Until recently, neuromyelitis optica (NMO) spectrum disorder and myelin oligodendrocyte glycoprotein (MOG) antibody disease represented variants...
Progressive Multifocal Leukoencephalopathy (PML) is a demyelinating disease of the brain caused by the polyomavirus JC (JCV) in immunosuppressed people. Th... MA Lima,F Bernal-Cano,DB Clifford,... - 《J Neurol Neurosurg Psychiatry》 被引量: 85发表: 2010年 "Benign" Imaging Abnormalities in Chi...
The Influence of the Proinflammatory Cytokine, Osteopontin, on Autoimmune Demyelinating Disease Large focal tumor-like demyelinating lesions of the brain: intermediate entity between multiple sclerosis and acute disseminated enc... Intramuscular interferon beta-1a therapy initiated during a first demyelinating...
In this context, it is understandable that edema and tissue pressure receive little notice as a cause for the development of demyelinating lesions. Nevertheless, Oppenheimer described that in cases of neuromyelitis optica (Devic’s disease), a necrosis resulted due to compression-ischemia secondary to...