Inflammatory demyelinating diseases (IDDs) are among the main causes of inflammatory and neurodegenerative injury of the central nervous system (CNS) in young adult patients. Of these, multiple sclerosis (MS) is the most frequent and studied, as it affects about a million...
Mild cerebral atrophy is the first and sometimes only imaging feature of the disease, which is also known as AIDS dementia complex, HIV dementia, HIV-associated dementia complex, and HIV- associated neuron-cognitive disorder (HAND). Involvement of the central white matter, basal ganglia, and...
1、 中枢神经系统脱髓鞘疾病 Demyelinating Diseases of the Central Nervous System 哈医大二院神经科 Chapter 1 Intraduction1. Concept A group of diseases of the brain and spinal cord in which demyelination is a prominent feature. 2. Pathologic Findings Destruction of the myelin sheaths of nerves; ...
Several authors relate to demyelinating disorders other secondary demyelinating conditions of other aetiologies, such as nutritional and vitamin deficiency, osmotic impairments (central pontine myelinolysis, Marchiafava- Bignami disease and others), genetic abnormalities (cerebral autosomal dominant arteriopathy ...
The demyelinating diseases are common neurological disorders that affect the central nervous system (CNS) and peripheral nervous system. They cause substantial disability and some are associated with a high mortality rate if not treated promptly. CNS demyelinating diseases discussed in this article include...
Demyelinating diseases are a group of disorders of the nervous system that involve loss of the myelin sheath that normally surrounds the neurons. Demyelinating diseases can affect both the central nervous system and peripheral nervous system.Related...
Demyelinating Disease Types Classification of the demyelinating diseases is done on the basis of whether they are affecting the nerves of the central nervous system or of the peripheral nervous system. Central Nervous System Diseases resulting from demyelination of the central nervous system (CNS) nerve...
Central Nervous System Expression of IL-10 Inhibits Autoimmune Encephalomyelitis Multiple sclerosis, an inflammatory, demyelinating disease of the CNS currently lacks an effective therapy. We show here that CNS inflammation and clinical disease in experimental autoimmune encephalomyelitis, an experimental model...
Figure 29.41.Central nervous system (CNS)–directed autoimmunity in demyelinating disease. T cells are activated in the periphery by antigen-presenting cells through the interaction of the T cell receptor (TCR) and antigen bound to major histocompatibility complex (MHC) class II along with coregula...
Method Of Treating Demyelinating Central Nervous System Diseases The invention provides a method of treating a subject afflicted with a disease associated with demyelination of the central nervous system comprising administering to the subject a therapeutically effective amount of any of a composition... ...