The prototypical inflammatory demyelinating disease of the CNS is MS, which is traditionally considered to be due to aberrant myelin-reactive T cells that, once activated in the periphery, gain entry to the CNS across a damaged blood鈥揵rain barrier. Recent studies, however, indicate that rather...
The prototypical inflammatory demyelinating disease of the CNS is MS, which is traditionally considered to be due to aberrant myelin-reactive T cells that, once activated in the periphery, gain entry to the CNS across a damaged blood–brain barrier. Recent studies, however, indicate that rather ...
The Spectrum of Demyelinating Inflammatory Diseases of the Central Nervous System Multiple sclerosis (MS) is, by far, the most common inflammatory demyelinating disease of the central nervous system (CNS), but it is not the only CNS infl... B Brochet 被引量: 0发表: 2015年 Studies on copper...
Myelin is mainly found around the axon of a nerve. It develops with the growth of the nerve, forming a protective insulating coat around it. The demyelination of nerves seriously affects the movements, cognition, sensation and other functions of patients. The Demyelinating Disease Image Source:wiki...
14、te or subacute demyelinating disease involved optic N and spinal cord at the same time.2.Etiology And Pathogenesis :与遗传素质和种族差异有关。西方-脑干;东方-视神经和脊髓;25%MS突发球后视神经炎;多方研究证实白种人对MS易感;非白种人对NMO易感。3.Pathology:Demyelination,plaque of sclerosis, in...
Figure 29.41.Central nervous system (CNS)–directed autoimmunity in demyelinating disease. T cells are activated in the periphery by antigen-presenting cells through the interaction of the T cell receptor (TCR) and antigen bound to major histocompatibility complex (MHC) class II along with coregul...
9.Relapsing-remitting multiple sclerosis is an inflammatory demyelinating disease of the CNS that is presumed to have an autoimmune cause. 复发缓和多发性硬化是一种炎性中枢系统脱髓鞘疾病,推测由自身免疫引起。 10.Objective:To analyze the CT and MRI manifestations of demyelinating pseudotumor of the brai...
demyelinating disease 神经纤维的髓鞘脱失而神经细胞相对甚少受累的一类疾病。病因不同,临床表现各异,但具有共同的病理特征。这类疾病分为两组,即髓鞘形成障碍型和髓鞘破坏型。髓鞘形成障碍型脱髓鞘疾病是遗传代谢缺陷引起的髓鞘形成障碍,主要包括髓鞘磷脂代谢异常引起的脑白质营养不良,如异染性白质脑病、脑白质海绵样...
MS is a chronic inflammatory neurodegenerative demyelinating disease of the CNS that is usually relapsing remitting at onset. There has been significant recent interest and progress in these disorders culminating in the creation of consensus definitions by the International Paediatric Multiple Sclerosis ...
Owing to the heterogeneity of patients with CNS demyelinating diseases, there is no clinical treatment that can adequately control all disease subtypes. Although significant progress has been made for relapsing–remitting MS, effective management of the progressive phase of MS has not yet been achieved...