Define deamination. deamination synonyms, deamination pronunciation, deamination translation, English dictionary definition of deamination. tr.v. de·am·i·nat·ed , de·am·i·nat·ing , de·am·i·nates To remove an amino group, NH2, from . de·am′i
Cytosine deamination produces mismatched uracil (U), which can be removed by uracil glycosylase , whereas m~5C deamination generates a G T mispair that cannot be processed by this enzyme. Correction of m~5CpG路TpG mismatches may instead be initiated by the thymine DNA glycosylase, TDG. Here ...
The APOBEC3 family of cytosine deaminase enzymes are able to restrict replication of retroelements, such as LINE-1. However, each of the seven APOBEC3 enzymes have been reported to act differentially to prevent LINE-1 retrotransposition and the mechanisms of APOBEC3-mediated LINE-1 inhibition has...
Nandy P, Periclou A, Avramis V (1997) The synergism of 6-mercaptopurine plus cytosine arabinoside followed by PEG-asparaginase in human leukemia cell lines (CCRF/CEM/0 and (CCRF/CEM/ara-C/7A) is due to increased cellular apoptosis. Anticancer Res 18:727–737 Google Scholar Ngan C-H, ...