When using pairs of spectra for de novo peptide sequencing, the most popular methods are designed for CID (or HCD) and ECD (or ETD) spectra because of the complementarity between them. Less attention has been paid to the use of CID and HCD spectra pairs. In this study, a new de novo...
必应词典为您提供de-novo-peptide-Sequencing的释义,网络释义: 多肽从头测序;测序;
图2. 充分利用de novo测序 的标准PEAKS Studio工作流程 参考文献 1.Tran NH, Qiao R, Xin L, Chen X, Liu C, Zhang X, Shan B, Ghodsi A, Li M. Deep learning enablesde novopeptide sequencing from data-independent-acquisition mass spectrometry. Nature Methods. 16(1), 63-66. 20/12/2018. 2...
所以肽段recall 更能体现它的性能。故使用SMSNet不进行rescoring的情况分别与PointNovo是否搭载LSTM模块的...
[名词解释] De novo sequencing(从头测序) 相关知识点: 试题来源: 解析 unknow peptide从头测序为蛋白质组研究提供了一种不用借助于任何蛋白质序列数据库信息,直接解读串联质谱数据的方法。其基本算法主要由4个部分组成:质谱图的构建、离子类型的确定、测序算法以及打分算法。
We present DeepNovo-DIA, a de novo peptide-sequencing method for data-independent acquisition (DIA) mass spectrometry data. We use neural networks to capture precursor and fragment ions across m/z, retention-time, and intensity dimensions. They are then further integrated with peptide sequence patte...
We present DeepNovo-DIA, a de novo peptide-sequencing method for data-independent acquisition (DIA) mass spectrometry data. We use neural networks to capture precursor and fragment ions across m/z, retention-time, and intensity dimensions. They are then further integrated with peptide sequence ...
期刊名:Molecular & Cellular Proteomics 发表时间:(2019年12月) IF:4.828 单位: 朱拉隆功大学 费城威斯塔研究所 物种:人 技术:de novo从头测序,深度学习 一、 概述: 该研究开发了一种基于深度学习的肽段从头测序框架SMSNet,在保持
We introduce DeepNovoV2, the state-of-the-art neural networks based model for de novo peptide sequencing. Contrary to existing models like DeepNovo or DeepMatch which represents each spectrum as a long sparse vector, in DeepNovoV2, we propose to directly represent a spectrum as a set of (m/...
MALDI-MS/MS analysis of these peptides yielded CID spectra with clear and often complete sequence ladders of b-ions. To test the applicability for de novo sequencing we next separated an ostrich muscle tissue protein lysate by one-dimensional SDS-PAGE. A protein band at 42 kDa was in-gel ...