2.Newell, E.W., et al. Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes. Immunity. 36 (1): 142-152, 2012. 3.Bendall, S.C., et al. Single-cell mass cytometry of differential immune and dru...
Newell EW, Sigal N, Bendall SC, Nolan GP, Davis MM. Cytometry by time-of- flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8 + T cell phenotypes. Immunity 2012;36 (1):142-52.Newell, Evan W., Sigal, N., Bendall, Sean C., Nolan,...
Mass cytometry, also known as cytometry by time-of-flight (CyTOF), fuses the experimental platforms offlow cytometryand elemental mass spectrometry. Mass cytometers require antibodies conjugated to rare earth metal isotopes of defined atomic mass instead of fluorochromes. Although throughput and sensiti...
It's called CyTOF, which stands for cytometry by time-of-flight, and it gives researchers greater insight into the intricacies of immunecellsthan ever before. Established at Yale last year, the CyTOF tool is one of an estimated 90 in use by researchers and pharmaceutical companies around the ...
Mass cytometry, also known as cytometry by time-of-flight (CyTOF), fuses the experimental platforms offlow cytometryand elemental mass spectrometry. Mass cytometers require antibodies conjugated to rare earth metal isotopes of defined atomic mass instead of fluorochromes. Although throughput and sensiti...
Mass cytometry, also known as CyTOF (Cytometry by Time-Of-Flight) combines the principles of flow cytometry with mass spectrometry to enable high-dimensional analysis of individual cells. This technology provides unparalleled detail, making it ideal for understanding complex cellular processes and interac...
CyTOF®, also known as mass cytometry, takes advantage of the low spectral overlap between heavy metal isotopes. In this technique, heavy metals are conjugated to antibodies, and their unique mass signatures are detected by time-of-flight mass spectrometry. Heavy metals take the place of fluorop...
approach and utilizes a time-of-flight mass spectrometer. In mass cytometry, cells are labeled with antibodies tagged with highly purified, stable isotypes and are then quantified using time-of-flight mass spectrometry[119]. It measures the abundance of the metal isotopes conjugated to the ...
Mass cytometry (or Cytometry by Time Of Flight mass spectrometry, CyTOF) has already been employed in clinical studies to comprehensively survey patients' circulating immune system. As interest in the "bedside" application of mass cytometry is growing, the delineation of relevant methodological issues ...
Mass cytometry, or Cytometry by Time-Of-Flight, is a powerful new platform for high-dimensional single-cell analysis of the immune system. It enables the simultaneous measurement of over 40 markers on individual cells through the use of monoclonal antibodies conjugated to rare-earth heavy-metal is...