CX3CR1 dose-dependently modulated monocyte-contact-dependent gene expression in human endothelium.在肾功能衰竭患者中,移植后一年内,CD16 单核细胞计数升高,并动态下降,主要原因是CD14 CD16 细胞减少。CX3CR1配体CX3CL1在患有...
Human umbilical vein endothelial cells (HUVECs) differentiate human CD14highCD16−monocytes into CD14+CD16+monocytes along with high expression of CX3CR1. (a) Specific monocyte subsets were separated in human liver MNCs and peripheral blood mononuclear cells (PBMCs). (b,c) Human CD14highCD16...
GMA effectively depletes CD14 + CD16 + monocytes and concomitantly increases CD14 hi CD16 CCR2 low "immature" monocytes; thus GMA was associated with the emergence of less inflammatory monocyte phenotype in circulation. 展开 关键词: Ulcerative colitis CD14+CD16+ monocytes CD14hiCD16−CCR2low ...
Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors. Immunity 33, 375–386 (2010). Article CAS PubMed PubMed Central Google Scholar Ellery, P.J. et al. The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 ...
. Human counterparts of Ly6Chighand Ly6Clowmonocytes are defined as CD14++/CD16−and CD14+/CD16++[175,176]. The main source of knowledge regarding the direct functioning of the CX3CL1/CX3CR1 axis in TBI and SCI is studies on animal models which were subjected to substitution on one ...
Background: Peripheral blood monocytes can be subdivided into different subsets based on the CD14/CD16 surface characteristics. Monocytes are a major source of cytokine secretion of pro-inflammatory immune responses, whereas CD16 monocyte subsets can also contribute to persistent inflammation in the ...
Furthermore, we defined classical and non-classical monocytes based on their surface expression of Ly6C and quantified the expression of CX3CR1high-expressing cells on both monocyte subsets. While there was no significant difference in the expression of CX3CR1 when using anti-CX3CR1 antibodies,...
. Human counterparts of Ly6Chighand Ly6Clowmonocytes are defined as CD14++/CD16−and CD14+/CD16++[175,176]. The main source of knowledge regarding the direct functioning of the CX3CL1/CX3CR1 axis in TBI and SCI is studies on animal models which were subjected to substitution on one ...