These findings suggest that CCR2 on CD14(+)CD16(+) monocytes may be a peripheral blood biomarker of HAND, indicative of increased HIV infected CD14(+)CD16(+) monocyte entry into the CNS that possibly increases the macrophage viral reservoir and contributes to HAND.Veenstra, Mike...
(B) Quantification of CD116 expression on the monocyte subsets of P1–P5 and local (LC, n = 3) and travel (TC, n = 1) controls. (C) FACS plots depicting the amounts of pSTAT5 induced by GM-CSF (20 ng/mL) or IL-3 (100 ng/mL) in CD14+ monocytes from healthy controls, P1...
摘要: Monocytes have been categorized in three main subpopulations based on CD14 and CD16 surface expression. Classical monocytes express the CD14(++)CD16(-)CCR2(+) phenotype and migrate to inflammatory...关键词: macrophages AIDS DOI: 10.1189/jlb.1111579 ...
There was no demonstrable impact on log-transformed baseline monocyte CD14+16+ subpopulations, baseline C-reactive protein, or baseline MCP-1 on log-change UACR at week 12, due to the lack of a strong treatment effect of PF-04634817 at that time point. A marked and sustained increase in se...
(CD11b+F4/80+) accumulated in the lamina propria, but neutrophils (CD11b+Ly6G+) were not significantly affected (Fig.5I–L). Therefore, the therapeutic effect of 3D5 on colitis may result from reducing monocyte/macrophage accumulation; in other words, PSMP might participate in colitis via ...
ArticleCASPubMedGoogle Scholar Tapp, L.D., Shantsila, E., Wrigley, B.J., et al., The CD14++CD16+monocyte subset and monocyte-platelet interactions in patients with ST-elevation myocardial infraction, Author information Authors and Affiliations ...
The surface expressions of CCR2, CX3CR1, CD64 and CD62L were measured in the three monocyte subsets (classical, non-classical and intermediate) by flow cytometry.ResultsThe percentages of CCR2 and CD62L on CD14+CD16 classical monocytes were significantly lower in ALS patients than in HC (...
学术范 onAcademic redjournal.org (全网免费下载) valueinhealthjournal.com (全网免费下载) jns-journal.com (全网免费下载) 查看更多 相似文献Functional Contribution of Elevated Circulating and Hepatic Non-Classical CD14+CD16+ Monocytes to Inflammation and Human Liver Fibrosis Monocyte-derived macrophages cri...
Besides routine clinic laboratory evaluation, to determine subtypes and activation status of monocytes, flow cytometry analyzes were performed on peripheral blood. In multi- colored analyze CD14-FITC, CD16-PE and CCR2-PerCP were used. Monocyte percentages and monocyte subtype were determined. CCR2 ...
We acquired cells using the BD FACS Canto II, acquiring 10,000 monocyte events in triplicate. We categorized monocyte subsets according to CD14 and CD16 expression: CD14++CD16−, classical monocytes; CD14++CD16+, intermediate monocytes; CD14+CD16+, nonclassical monocytes (Figure 1). Whereas ...