Photochemical generation of dibenzosilacyclohept-4-yne 3 from the corresponding cyclopropenone 1 and its copper-free click reactions are reported. Steady-state irradiation, kinetic, and transient absorption spectroscopy studies revealed that strained alkyne 3 is rapidly (<5 ns) and efficiently (桅 =...
Cu-freeclick chemistry
The copper(I)-catalysed azide–alkyne cycloaddition (the CuAAC ‘click’ reaction) is proving to be a powerful new tool for the construction of mechanically interlocked molecular-level architectures. The reaction is highly selective for the functional groups involved (terminal alkynes and azides) and...
tuberculosis, among which a per-acetylated glycosyl quinoline hybrids showed better activity than a carbohydrate-free control compound.76 In addition to the discussed triazolyl carbohydrates with antimicrobial activities, click derivatization was carried out on conventional antibiotics scaffolds, such as amino...
A new [2]catenane containing four Rh(III) porphyrins has been prepared following a three-step strategy: (i) Cu(I)-driven entwining of two free base porphyrin-bearing bidentate chelates, followed by (ii) insertion of rhodium in the porphyrin nuclei, and finally (iii) cyclisation via the form...
Z. Click polymerization: facile synthesis of functional poly(aroyltriazole)s by metal-free, regioselective 1,3-dipolar polycycloaddition. Macromolecules 40, 2308–2317 (2007). Article CAS Google Scholar Binauld, S., Boisson, F., Hamaide, T., Pascault, J. P., Drockenmuller, E. & ...
In this article, we reported a new enzyme-free SERS immunoassay by utilizing plasmonic Cu2- xS ySe1- y nanoparticles (NPs) as nanocatalyst to catalyze the click chemistry between the azido and alkynyl substrate which is used as the SERS signal reporter. The unique vibration of C≡C ...
This scaffold holds two alkyne arms in a free and TIPS-protected form for consecutive CuAAC (copper(I)-catalyzed azide鈥揳lkyne cycloadditi... Fabre,Benjamin,Pícha,... 被引量: 2发表: 2015年 New Stable Cu(I) Catalyst Supported on Weakly Acidic Polyacrylate Resin for "Click" Chemistry: ...
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of Cu in the reaction (Fig.1b)6. In addition, oxidative damage of biomolecules is a significant issue associated with current CuAAC-based bioconjugation strategies, severely limiting development9,10,11. These issues have inspired the development of a series of alternative Cu-free click approaches...