A heterobifunctional linker with DBCO and NHS ester function groups flanking PEG6 (hexaethylene glycol). Show pricing DBCO-STP ester Activated ester for modification of proteins/antibodies/peptides followed by introduction into copper-free click chemistry reaction. Show pricing ...
■ Copper-free Click Chemistry (DBCO & BCN reagents) Conventional "Click Chemistry" requires the presence of a Cu(I) catalyst that is toxic to most organisms and thus, prevents its use in many biological systems. The novel Copper-free Click Chemistry is based on the reaction of a diary...
copper-free click reactionlinear internal alkyneordered hexagonal columnar mesophaseplastic hexagonal columnar mesophaseClick chemistry continues to attract much attention and is widely used in a variety of synthetic areas. However, it is a challenge to do this type of reaction in the absence of a ...
Reactivity of Biarylazacyclooctynones in Copper-Free Click Chemistry The 1,3-dipolar cycloaddition of cyclooctynes with azides, also called "copper-free click chemistry", is a bioorthogonal reaction with widespread applicati... CG Gordon,JL Mackey,JC Jewett,... - 《Journal of the American Chemi...
click chemistry reaction, the researchers can safely use their reaction in living organisms. Compared to the copper-free click chemistry reaction, which can take up to an hour, the ligand-accelerated copper-catalyzed click chemistry reaction can achieve effective labeling within 3-5 minutes. The ...
Click-iT sDIBO Alkyne labels react with azides via a copper-free Click chemistry reaction to form a stable triazole linkage with an Alexa Fluor, Biotin, or label of your choice. Copper-free click reactions using our sDIBO alkynes are ideal for surface labeling of live cells; they also minim...
Click-iT sDIBO Alkyne labels react with azides via a copper-free Click chemistry reaction to form a stable triazole linkage with an Alexa Fluor, Biotin, or label of your choice. Copper-free click reactions using our sDIBO alkynes are ideal for surface labeling of live cells; they also minim...
Bioorthogonal coupling approaches such as the well-established copper-catalyzed azide-alkyne cycloaddition (CuAAC) "click" reaction are attractive alternatives as the reaction kinetics are favorable and azide-containing reagents are widely available. In the work described here, we prepared li...
is a widely used molecule in click chemistry reactions. Compared with traditional copper catalyzed click reactions, the click reactions involving DBCO do not require the participation of copper ions, thus avoiding the potential toxicity issues caused by copper ions and making the reaction conditions mil...
Click-iT sDIBO Alkyne labels react with azides via a copper-free Click chemistry reaction to form a stable triazole linkage with an Alexa Fluor, Biotin, or label of your choice. Copper-free click reactions using our sDIBO alkynes are ideal for surface labeling of live cells; they also minim...