tothetumor-bearingmicebyintratumorinjectionofanisomycinordoxorubicin.Results:AnisomycininhibitedsignificantlyCT26cellproliferation.TheCT26cellcycleentrywasmainlyblockedatS-phasewiththeenhancementoftheSub-G0/G1-phaseproportionandtheCT26cellapoptosiswasincreasedbyanisomycin.ThetumorvolumewasreducedintheCT26-bearingmicetreated...
tumor-bearing mice with the oral gavage ofproteus mirabilis. although no significant inhibitory effect on tumor growth was observed, the oral gavage ofproteus mirabiliswas associated with the decreased percentage of proliferated tumor-specific cd8+t cellsin vitro. conclusionsbroad-spectrum antibiotics ...
The MENK-treated tumor mice showed normalized liver function with glycolipid metabolic homeostasis. No inhibitory effect on CT26 tumor cell in vitro, but only reduced lipid synthesis in AML12 were presented by MENK. Meanwhile, MENK invigorated immune response in both two animal models by markedly ...
plantarum inhibited CT26 cell growth in BALB/c mice and prolonged the survival time of tumour-bearing mice compared with mice administered L. rhamnosus. L. plantarum produced protective immunity against the challenge with CT26 cells by increasing the effector functions of CD8+ and natural killer ...
The Cca mass size was significantly reduced, or radically disappeared (5 out of 10; or 50%); the survival rate was markedly improved in mice immunized with Cca-extract, but not in those immunized with another tumor cell (U87 cell) extracts or to bovine serum albumin. The immunization with...
99. We could confirm this findings and translate it to another tumor model using plasma-treated saline. However, many studies used plasma-treated cell culture medium to inactivate cancer cells100,101,102. While this is an approach proven to be effective also in tumor-bearing mice24,25,100, ...
Methods Flow-sorted bone marrow MDSCs from Balb/c mice bearing CT26 tumor xenograft were treated with either C-K or PBS for 96 h and examined for apoptosis with Annexin V/7-AAD, Cox-2 and Arg-1 expressions using qRT-PCR, and supernatant IL-1β, IL-6, and IL-17 levels with ELISA....
NLG919经灌胃给药,100 mg/kg,BID;CPT经腹腔注射给药,50 mg/kg,每3天1次;给药后每3天测量1次动物体重(n=12).图2 NLG919联用CPT对CT26荷瘤小鼠体重的影响Fig.2 Effects of combination of NLG919 and CPT on body weight of CT26-bearing mice 表1 NLG919联用CPT对CT26荷瘤小鼠体重及瘤重的影响(n=12...
Purpose:To investigate whether the percentage of apparent diffusion coefficient (ADC) changes could be used as an imaging marker related to tumor cell apoptotic and Ki-67 proliferation index of tumors.Materials and Methods:Mice bearing CT26 colorectal carcinoma tumors were scanned before radiotherapy, ...
CT26/NIS-cODC cells implanted into mice underwent PET imaging, and tumor-bearing mice were treated with BTZ alone or with BTZ plus 131I. CT26/NIS-cODC cells accumulated NIS protein, which led to high radioiodine uptake when proteasome activity was inhibited or after enrichment for stemness. ...