The present study sets out to systematically investigate the variation of TGI for ICB treatment in syngeneic mouse models, using tumor growth data of anti-PD-1 treatment in the CT26.WT syngeneic mouse model for 27 independent studies.METHODS: For each study, we calculated TGI and median area ...
Model Information:Synonyms: CT-26, CT26 CT26.WT was cloned from an N-nitroso-N-methylurethane (NMU) induced, undifferentiated colon carcinoma murine cell line. The cell line has an H-2d haplotype and can be grown in the BALB/c mouse strain. As a mainstay model for evaluating surrogate ...
Syngeneic Models GEMM-Derived Allografts Humanized Mice CDX Models PDX Models Humanized Drug Target IO Mice Nervous System Disease Parkinson's Disease Mouse Model Mouse Model of Lumbocrural Pain Autoimmune Disease Psoriasis Mice EAE Mice Digestive System Disease Intestinal Inflammation ...
The genO‑hPD-1/hPD-L1 mouse model enables in vivo efficacy assessment and profiling of molecules targeting the human PD-1/PD-L1 axis in fully immunocompetent mice. genO-hPD‑1/hTIM3 The genO‑hPD‑1/hTIM3 mouse enables the in vivo efficacy assessment and profiling of immuno-oncolog...
Herein, the binding characteristics of the cmHsp70.1 mouse monoclonal antibody (mAb) were evaluated in vitro and in a syngeneic tumour mouse model. More than 50% of the CT26 mouse colon carcinoma cells express Hsp70 on their cell surface at 4°C. After a temperature shift to 37°C, the ...
Syngeneic Models GEMM-Derived Allografts Humanized Mice CDX Models PDX Models Humanized Drug Target IO Mice Nervous System Disease Parkinson's Disease Mouse Model Mouse Model of Lumbocrural Pain Autoimmune Disease Psoriasis Mice EAE Mice Digestive System Disease Intestinal Inflammation ...
Figure 3. Body weight change of CT26-hCD24 syngeneic model Ⅲ.Expression of hCD24 protein in tumors Figure 4. The expression of hCD24 in humanized modified tumors by FACS相关品系 E.G7-OVA-hCD24 细胞系名称:E.G7-OVA-hCD24 目录号:NM-S40-TM01 CT26-hCD24/hPDL1 细胞系名称:CT26-CD...
Herein, the binding characteristics of the cmHsp70.1 mouse monoclonal antibody (mAb) were evaluated in vitro and in a syngeneic tumour mouse model. More than 50% of the CT26 mouse colon carcinoma cells express Hsp70 on their cell surface at 4掳C. After a temperature shift to 37掳C, the ...
not alter median ADC in either CT26 or 4T1 models, although diffusion heterogeneity, measured by the IQR of ADC was increased markedly in 3/7 CT26 tumors.In conclusion, our data are the first to evaluate ADC changes induced by RT and immunotherapy agents in syngeneic mouse models of cancer....
FujiiHitoshiOhmoriPathobiology : journal of immunopathology, molecular and cellular biologyKawahara I, Mori T, Goto K, Fujii K, Ohmori H, Kishi S, Fujiwara-Tani R, Kuniyasu H. Fatty acids induce Stemness in the stromal cells of a CT26 mouse tumor model. Pathobiology. 2017;84(5):237-42....