A critical overview of the catalytic joining of two different electrophiles, cross-electrophile coupling (XEC), is presented with an emphasis on the central challenge of cross-selectivity. Recent synthetic advances and mechanistic studies have shed light on four possible methods for overcoming this cha...
In this mini‐review, we have systematically summarized the most recent advances in electroreductive cross‐electrophile coupling (eXEC) reactions during the last decade. Our focus has been on readily available electrophiles, including aryl and alkyl organic (pseudo)halides, as well ...
The catalytic asymmetric construction of Csp3–Csp3 bonds remains one of the foremost challenges in organic synthesis1. Metal-catalysed cross-electrophile couplings (XECs) have emerged as a powerful tool for C–C bond formation2–5. However, coupling two
In recent years, nickel-mediated cross-electrophile (XEC) coupling has emerged as a potent strategy for constructing C(sp3)−C(sp3) bonds, utilizing various native and bench-stable aliphatic coupling entities, thus circumventing the use of moisture-sensitive organometallic species8,9,10,11,12,13...
Cross-electrophile coupling, the cross-coupling of two different electrophiles, avoids the need for preformed carbon nucleophiles, but development of general methods has lagged behind cross-coupling and C–H functionalization. A central reason for this slow development is the challenge of selectively co...
Kumada-Tamao-Corriu coupling reaction catalyzed by transition-metal has been widely used in organic synthesis. Organic halides are mostly used as electrophiles in this reaction. Compared with organic halides, O-based electrophiles are less explored. In this review, we summarized the Kumada-Tamao-Cor...
1 | Cross-electrophile C − Si coupling reactions. a TM-catalyzed XEC of chlorosilanes. b This work: XEC of alkynyl sulfides with chlorosilanes. appropriate alkynyl electrophile and metal catalyst was the key to achieve the XEC between alkynyl electrophiles and chlorosilanes. Easily synthesized ...
ChemInform Abstract: Palladium-Catalyzed Cross-Coupling Reactions of Organoboronic Acids with Organic Electrophilesorganic chemistry, reviewcatalysis, phase-transfer catalysissubstitution reactionsorgano-boron compoundsChemInform is a weekly Abstracting Service, delivering concise information at a glance that was ...
(5) For a comprehensive recent review on cross-coupling reactions of secondary alkyl electrophiles, see: (a) Rudolph, A.; Lautens, M. Angew. Chem... Fairlamb 被引量: 196发表: 1998年 Room-Temperature Insertion of Elemental Tellurium into the Csp3Br and I Bonds of α-Bromo- and α-Io...
ChemInform Abstract: Reductive Cross-Coupling Reactions Between Two Electrophilesdoi:10.1002/chin.201436247organic chemistryreviewC-C bond formationolefinationReview: [state of the art, recent protocols and important mechanistic studies; 50 refs.Christiane E. I. Knappke...