Cross-Electrophile Coupling of Unactivated Alkyl Chlorides;Holt A. Sakai, Wei Liu, Chi “Chip” Le and David W. C. MacMillan*;J. Am. Chem. Soc.2020, 142, 27, 11691–11697;https://doi.org/10.1021/jacs.0c04812
Cross-Electrophile Coupling of Unactivated Alkyl Chlorides;Holt A. Sakai, Wei Liu, Chi “Chip” Le and David W. C. MacMillan*;J. Am. Chem. Soc.2020, 142, 27, 11691–11697;https://doi.org/10.1021/jacs.0c04812
参考资料 Cross-Electrophile Coupling of Unactivated Alkyl Chlorides;Holt A. Sakai, Wei Liu, Chi “Chip” Le and David W. C. MacMillan*;J. Am. Chem. Soc.2020, 142, 27, 11691–11697;https://doi.org/10.1021/jacs.0c
[6] László Kürti, Barbara Czakó.Strategic Applications of Named Reactions in Organic Synthesis; Elsevier,2005. [7] Takuya Suga et al., Nickel-Catalyzed Cross-Electrophile Coupling between Benzyl Alcohols and Aryl Halides Assisted by Titanium Co-reductant.Org. Lett.2018,20, 7846. [8] Xiaheng...
此方法利用更加廉价的氯代烷烃和氯代芳烃作为底物,有非常好的经济价值。 参考资料 Cross-Electrophile Coupling of Unactivated Alkyl Chlorides;Holt A. Sakai, Wei Liu, Chi “Chip” Le and David W. C. MacMillan*;J. Am. Chem. Soc.2020, 142, 27, 11691–11697;https:///10.1021/jacs.0c04812...
(Silyl Radical Activation of Alkyl Halides in Metallaphotoredox Catalysis: A Unique Pathway for Cross-Electrophile Coupling.J. Am. Chem. Soc.,2016,138, 8084-8087, DOI: 10.1021/jacs.6b04818) Scheme 1. 经由光氧化还原的烷基/芳基溴代物的偶联。图片来源:JACS...
9)Metallaphotoredox-Catalyzed Cross-Electrophile Csp 3 −Csp 3 Coupling of Aliphatic Bromides 10)Spin-Center Shift-Enabled Direct Enantioselective α‑Benzylation of Aldehydes with Alcohols 人才培养 Dave W. C. Macmillan作为目前化学学术界的活跃大牛,同时也培养了很多杰出的子弟,一下列举部分: ...
3)Direct arylation of strong aliphatic C–H bonds 4)Decarboxylative sp3 C–N coupling via dual copper and photoredox catalysis 5)Two-Step Synthesis of Carbohydrates by Selective Aldol Reactions 6)Discovery of an a-Amino C–H Arylation Reaction Using the Strategy of Accelerated Serendipity ...
Cross-Electrophile Coupling of Unactivated Alkyl Chlorides;Holt A. Sakai, Wei Liu, Chi “Chip” Le and David W. C. MacMillan*;J. Am. Chem. Soc.2020, 142, 27, 11691–11697;https://doi.org/10.1021/jacs.0c04812 由于微信更改了订阅号的推送规则,很多朋友不能快速找到我们,其实我们每天都在推送...
Cross-Electrophile Coupling of Unactivated Alkyl Chlorides;Holt A. Sakai, Wei Liu, Chi “Chip” Le and David W. C. MacMillan*;J. Am. Chem. Soc.2020, 142, 27, 11691–11697;https://doi.org/10.1021/jacs.0c04812 由...